Microglia: The constant gardeners

Microglia: The constant gardeners

Once thought to be passive sentinels, microglia now seem to be crucial for pruning back neurons during development.

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Bibliographische Detailangaben
Veröffentlicht in:Nature (London) 2012-05, Vol.485 (7400), p.570-572
1. Verfasser: Hughes, Virginia
Format: Artikel
Sprache:eng
Schlagworte:
631/378/2571
631/378/2596/1953
Animals
Autistic Disorder - immunology
Autistic Disorder - therapy
Brain - cytology
Brain - embryology
Brain - growth & development
Brain - pathology
Cell Movement
Complement System Proteins - immunology
Complement System Proteins - metabolism
Humanities and Social Sciences
Humans
Mice
Mice, Knockout
Microglia - cytology
Microglia - immunology
Microglia - physiology
Microglia - transplantation
multidisciplinary
Neurons - cytology
Neurons - immunology
Neurons - pathology
news-feature
Rett Syndrome - genetics
Rett Syndrome - therapy
Science
Science (multidisciplinary)
Synapses - pathology
Time-Lapse Imaging
Trichotillomania - therapy
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Beschreibung
Zusammenfassung:Once thought to be passive sentinels, microglia now seem to be crucial for pruning back neurons during development.
ISSN:0028-0836
1476-4687
DOI:10.1038/485570a