Blastocystis hominis as a contributing risk factor for development of iron deficiency anemia in pregnant women
Intestinal parasitic infection increases the risk of developing iron deficiency anemia (IDA) during pregnancy. The objective of this study was to assess Blastocystis hominis as a contributing risk factor for development of IDA in pregnant women. A total of 200 fecal specimens from 120 pregnant women...
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| Veröffentlicht in: | Parasitology research (1987) 2012-06, Vol.110 (6), p.2167-2174 |
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| description | Intestinal parasitic infection increases the risk of developing iron deficiency anemia (IDA) during pregnancy. The objective of this study was to assess
Blastocystis hominis
as a contributing risk factor for development of IDA in pregnant women. A total of 200 fecal specimens from 120 pregnant women with IDA (mean Hb = 9.6 g/dl), and 80 non-anemic controls were examined for
Blastocystis
. Fecal specimens were examined by the formalin/ethyl-acetate concentration technique, iron hematoxylin staining, modified Ziehl–Neelsen acid-fast staining, and by the in vitro cultivation technique for
Blastocystis
. Frequency of
Blastocystis
infection, detected microscopically and by the in vitro culture technique, was significantly higher in IDA study group (
n
= 48; 40%) compared to non-anemic controls (
n
= 5; 6.3%;
P
|
| doi_str_mv | 10.1007/s00436-011-2743-3 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1017989604</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A306240748</galeid><sourcerecordid>A306240748</sourcerecordid><originalsourceid>FETCH-LOGICAL-c441t-50dca0dbb5f50784c83cf70f45e0cfe0817d5f4030d53d4a73111fb46ccd30343</originalsourceid><addsrcrecordid>eNp9kd9rFDEQx4Mo9nr6B_giARF82TrZJJvdx1r8USj0pT6HbDY5U3eTM9mt3H_fOfZUBJEkTJj5TGYyX0JeMbhgAOp9ARC8qYCxqlaCV_wJ2TDB64p1Uj4lG-jwjlF-Rs5LuQdgqhHiOTmra9YorpoNiR9GU-ZkD2UOhX5LU4hoDW5qU5xz6Jc5xB3NoXyn3tg5ZerxDO7BjWk_uTjT5GnIKaLPBxtctAdqopuCoSHSfXa7aJD6mRB-QZ55Mxb38mS35Ounj3dXX6qb28_XV5c3lRWCzZWEwRoY-l56CaoVtuXWK_BCOrDeQcvUIL0ADoPkgzCKM8Z8LxprBw5c8C15t767z-nH4sqsp1CsG0dsLC1FMxxF13YNHNE3K7ozo9Mh-jRnY4-4vuTQ1AKUaJG6-AeFa8CP4qTw6-j_K4GtCTanUrLzep_DZPIBa-ujenpVT6M--qie5pjz-tT10k9u-J3xSy4E3p4AU6wZfTbRhvKHkx0XHY5lS-qVKxiKO5f1fVpyxIn_p_ojCROxiQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1017989604</pqid></control><display><type>article</type><title>Blastocystis hominis as a contributing risk factor for development of iron deficiency anemia in pregnant women</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>El Deeb, Hala K. ; Salah-Eldin, Hesham ; Khodeer, Seham</creator><creatorcontrib>El Deeb, Hala K. ; Salah-Eldin, Hesham ; Khodeer, Seham</creatorcontrib><description>Intestinal parasitic infection increases the risk of developing iron deficiency anemia (IDA) during pregnancy. The objective of this study was to assess
Blastocystis hominis
as a contributing risk factor for development of IDA in pregnant women. A total of 200 fecal specimens from 120 pregnant women with IDA (mean Hb = 9.6 g/dl), and 80 non-anemic controls were examined for
Blastocystis
. Fecal specimens were examined by the formalin/ethyl-acetate concentration technique, iron hematoxylin staining, modified Ziehl–Neelsen acid-fast staining, and by the in vitro cultivation technique for
Blastocystis
. Frequency of
Blastocystis
infection, detected microscopically and by the in vitro culture technique, was significantly higher in IDA study group (
n
= 48; 40%) compared to non-anemic controls (
n
= 5; 6.3%;
P
< 0.0001), and 26.5% (
n
= 53) in all study subjects. Among the 48 cases,
Blastocystis
without other intestinal parasitic infections was detected in 41 cases (34.2%), while seven cases (5.8%) with
Blastocystis
were coinfected with other intestinal parasites which included
Giardia
and
Cryptosporidium
(1.7% each), and
Entamoeba
sp.,
Ascaris
, and
Trichuris
(0.8% each). The mean Hb level of the 48
Blastocystis
-infected cases was 9.2 g/dl (mild anemia). While the other 72 IDA cases with no infection had mean Hb of 10.0 g/dl (mild anemia), with a significant difference in mean Hb level between
Blastocystis
-infected and the non-infected IDA cases (
P
< 0.0001). Furthermore, among the 48
Blastocystis
-infected IDA cases, the mean Hb of the 41
Blastocystis
-infected cases without other intestinal parasitic co-infection was 9.1 g/dl (mild anemia), while the mean Hb level of the 7
Blastocystis
-infected cases with other intestinal parasitic co-infection was 8.7 g/dl (moderate anemia). Findings of the current study showed that
B. hominis
infection contributes to the development of IDA in pregnant women. Hence, parasitological diagnostic tests are recommended in routine examination at all antenatal clinics.</description><identifier>ISSN: 0932-0113</identifier><identifier>EISSN: 1432-1955</identifier><identifier>DOI: 10.1007/s00436-011-2743-3</identifier><identifier>PMID: 22167376</identifier><identifier>CODEN: PARREZ</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Adult ; Anemia, Iron-Deficiency - epidemiology ; Anemia, Iron-Deficiency - etiology ; Animals ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedicine ; Blastocystis hominis - isolation & purification ; Blastocystis Infections - complications ; Blastocystis Infections - epidemiology ; Feces - parasitology ; Female ; Fundamental and applied biological sciences. Psychology ; General aspects ; General aspects and techniques. Study of several systematic groups. Models ; Health aspects ; Host-parasite relationships ; Humans ; Immunology ; Invertebrates ; Iron deficiency anemia ; Medical Microbiology ; Microbiology ; Microscopy - methods ; Original Paper ; Parasitology - methods ; Physiological aspects ; Pregnancy ; Pregnancy Complications, Infectious - parasitology ; Pregnant women ; Prevalence ; Protozoa ; Risk Factors</subject><ispartof>Parasitology research (1987), 2012-06, Vol.110 (6), p.2167-2174</ispartof><rights>Springer-Verlag 2011</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2012 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-50dca0dbb5f50784c83cf70f45e0cfe0817d5f4030d53d4a73111fb46ccd30343</citedby><cites>FETCH-LOGICAL-c441t-50dca0dbb5f50784c83cf70f45e0cfe0817d5f4030d53d4a73111fb46ccd30343</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00436-011-2743-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00436-011-2743-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25934940$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22167376$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El Deeb, Hala K.</creatorcontrib><creatorcontrib>Salah-Eldin, Hesham</creatorcontrib><creatorcontrib>Khodeer, Seham</creatorcontrib><title>Blastocystis hominis as a contributing risk factor for development of iron deficiency anemia in pregnant women</title><title>Parasitology research (1987)</title><addtitle>Parasitol Res</addtitle><addtitle>Parasitol Res</addtitle><description>Intestinal parasitic infection increases the risk of developing iron deficiency anemia (IDA) during pregnancy. The objective of this study was to assess
Blastocystis hominis
as a contributing risk factor for development of IDA in pregnant women. A total of 200 fecal specimens from 120 pregnant women with IDA (mean Hb = 9.6 g/dl), and 80 non-anemic controls were examined for
Blastocystis
. Fecal specimens were examined by the formalin/ethyl-acetate concentration technique, iron hematoxylin staining, modified Ziehl–Neelsen acid-fast staining, and by the in vitro cultivation technique for
Blastocystis
. Frequency of
Blastocystis
infection, detected microscopically and by the in vitro culture technique, was significantly higher in IDA study group (
n
= 48; 40%) compared to non-anemic controls (
n
= 5; 6.3%;
P
< 0.0001), and 26.5% (
n
= 53) in all study subjects. Among the 48 cases,
Blastocystis
without other intestinal parasitic infections was detected in 41 cases (34.2%), while seven cases (5.8%) with
Blastocystis
were coinfected with other intestinal parasites which included
Giardia
and
Cryptosporidium
(1.7% each), and
Entamoeba
sp.,
Ascaris
, and
Trichuris
(0.8% each). The mean Hb level of the 48
Blastocystis
-infected cases was 9.2 g/dl (mild anemia). While the other 72 IDA cases with no infection had mean Hb of 10.0 g/dl (mild anemia), with a significant difference in mean Hb level between
Blastocystis
-infected and the non-infected IDA cases (
P
< 0.0001). Furthermore, among the 48
Blastocystis
-infected IDA cases, the mean Hb of the 41
Blastocystis
-infected cases without other intestinal parasitic co-infection was 9.1 g/dl (mild anemia), while the mean Hb level of the 7
Blastocystis
-infected cases with other intestinal parasitic co-infection was 8.7 g/dl (moderate anemia). Findings of the current study showed that
B. hominis
infection contributes to the development of IDA in pregnant women. Hence, parasitological diagnostic tests are recommended in routine examination at all antenatal clinics.</description><subject>Adult</subject><subject>Anemia, Iron-Deficiency - epidemiology</subject><subject>Anemia, Iron-Deficiency - etiology</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Blastocystis hominis - isolation & purification</subject><subject>Blastocystis Infections - complications</subject><subject>Blastocystis Infections - epidemiology</subject><subject>Feces - parasitology</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>General aspects and techniques. Study of several systematic groups. Models</subject><subject>Health aspects</subject><subject>Host-parasite relationships</subject><subject>Humans</subject><subject>Immunology</subject><subject>Invertebrates</subject><subject>Iron deficiency anemia</subject><subject>Medical Microbiology</subject><subject>Microbiology</subject><subject>Microscopy - methods</subject><subject>Original Paper</subject><subject>Parasitology - methods</subject><subject>Physiological aspects</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - parasitology</subject><subject>Pregnant women</subject><subject>Prevalence</subject><subject>Protozoa</subject><subject>Risk Factors</subject><issn>0932-0113</issn><issn>1432-1955</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kd9rFDEQx4Mo9nr6B_giARF82TrZJJvdx1r8USj0pT6HbDY5U3eTM9mt3H_fOfZUBJEkTJj5TGYyX0JeMbhgAOp9ARC8qYCxqlaCV_wJ2TDB64p1Uj4lG-jwjlF-Rs5LuQdgqhHiOTmra9YorpoNiR9GU-ZkD2UOhX5LU4hoDW5qU5xz6Jc5xB3NoXyn3tg5ZerxDO7BjWk_uTjT5GnIKaLPBxtctAdqopuCoSHSfXa7aJD6mRB-QZ55Mxb38mS35Ounj3dXX6qb28_XV5c3lRWCzZWEwRoY-l56CaoVtuXWK_BCOrDeQcvUIL0ADoPkgzCKM8Z8LxprBw5c8C15t767z-nH4sqsp1CsG0dsLC1FMxxF13YNHNE3K7ozo9Mh-jRnY4-4vuTQ1AKUaJG6-AeFa8CP4qTw6-j_K4GtCTanUrLzep_DZPIBa-ujenpVT6M--qie5pjz-tT10k9u-J3xSy4E3p4AU6wZfTbRhvKHkx0XHY5lS-qVKxiKO5f1fVpyxIn_p_ojCROxiQ</recordid><startdate>20120601</startdate><enddate>20120601</enddate><creator>El Deeb, Hala K.</creator><creator>Salah-Eldin, Hesham</creator><creator>Khodeer, Seham</creator><general>Springer-Verlag</general><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120601</creationdate><title>Blastocystis hominis as a contributing risk factor for development of iron deficiency anemia in pregnant women</title><author>El Deeb, Hala K. ; Salah-Eldin, Hesham ; Khodeer, Seham</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c441t-50dca0dbb5f50784c83cf70f45e0cfe0817d5f4030d53d4a73111fb46ccd30343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Anemia, Iron-Deficiency - epidemiology</topic><topic>Anemia, Iron-Deficiency - etiology</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Blastocystis hominis - isolation & purification</topic><topic>Blastocystis Infections - complications</topic><topic>Blastocystis Infections - epidemiology</topic><topic>Feces - parasitology</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>General aspects and techniques. Study of several systematic groups. Models</topic><topic>Health aspects</topic><topic>Host-parasite relationships</topic><topic>Humans</topic><topic>Immunology</topic><topic>Invertebrates</topic><topic>Iron deficiency anemia</topic><topic>Medical Microbiology</topic><topic>Microbiology</topic><topic>Microscopy - methods</topic><topic>Original Paper</topic><topic>Parasitology - methods</topic><topic>Physiological aspects</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - parasitology</topic><topic>Pregnant women</topic><topic>Prevalence</topic><topic>Protozoa</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>El Deeb, Hala K.</creatorcontrib><creatorcontrib>Salah-Eldin, Hesham</creatorcontrib><creatorcontrib>Khodeer, Seham</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Parasitology research (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El Deeb, Hala K.</au><au>Salah-Eldin, Hesham</au><au>Khodeer, Seham</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blastocystis hominis as a contributing risk factor for development of iron deficiency anemia in pregnant women</atitle><jtitle>Parasitology research (1987)</jtitle><stitle>Parasitol Res</stitle><addtitle>Parasitol Res</addtitle><date>2012-06-01</date><risdate>2012</risdate><volume>110</volume><issue>6</issue><spage>2167</spage><epage>2174</epage><pages>2167-2174</pages><issn>0932-0113</issn><eissn>1432-1955</eissn><coden>PARREZ</coden><abstract>Intestinal parasitic infection increases the risk of developing iron deficiency anemia (IDA) during pregnancy. The objective of this study was to assess
Blastocystis hominis
as a contributing risk factor for development of IDA in pregnant women. A total of 200 fecal specimens from 120 pregnant women with IDA (mean Hb = 9.6 g/dl), and 80 non-anemic controls were examined for
Blastocystis
. Fecal specimens were examined by the formalin/ethyl-acetate concentration technique, iron hematoxylin staining, modified Ziehl–Neelsen acid-fast staining, and by the in vitro cultivation technique for
Blastocystis
. Frequency of
Blastocystis
infection, detected microscopically and by the in vitro culture technique, was significantly higher in IDA study group (
n
= 48; 40%) compared to non-anemic controls (
n
= 5; 6.3%;
P
< 0.0001), and 26.5% (
n
= 53) in all study subjects. Among the 48 cases,
Blastocystis
without other intestinal parasitic infections was detected in 41 cases (34.2%), while seven cases (5.8%) with
Blastocystis
were coinfected with other intestinal parasites which included
Giardia
and
Cryptosporidium
(1.7% each), and
Entamoeba
sp.,
Ascaris
, and
Trichuris
(0.8% each). The mean Hb level of the 48
Blastocystis
-infected cases was 9.2 g/dl (mild anemia). While the other 72 IDA cases with no infection had mean Hb of 10.0 g/dl (mild anemia), with a significant difference in mean Hb level between
Blastocystis
-infected and the non-infected IDA cases (
P
< 0.0001). Furthermore, among the 48
Blastocystis
-infected IDA cases, the mean Hb of the 41
Blastocystis
-infected cases without other intestinal parasitic co-infection was 9.1 g/dl (mild anemia), while the mean Hb level of the 7
Blastocystis
-infected cases with other intestinal parasitic co-infection was 8.7 g/dl (moderate anemia). Findings of the current study showed that
B. hominis
infection contributes to the development of IDA in pregnant women. Hence, parasitological diagnostic tests are recommended in routine examination at all antenatal clinics.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22167376</pmid><doi>10.1007/s00436-011-2743-3</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0932-0113 |
| ispartof | Parasitology research (1987), 2012-06, Vol.110 (6), p.2167-2174 |
| issn | 0932-0113 1432-1955 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1017989604 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Anemia, Iron-Deficiency - epidemiology Anemia, Iron-Deficiency - etiology Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Blastocystis hominis - isolation & purification Blastocystis Infections - complications Blastocystis Infections - epidemiology Feces - parasitology Female Fundamental and applied biological sciences. Psychology General aspects General aspects and techniques. Study of several systematic groups. Models Health aspects Host-parasite relationships Humans Immunology Invertebrates Iron deficiency anemia Medical Microbiology Microbiology Microscopy - methods Original Paper Parasitology - methods Physiological aspects Pregnancy Pregnancy Complications, Infectious - parasitology Pregnant women Prevalence Protozoa Risk Factors |
| title | Blastocystis hominis as a contributing risk factor for development of iron deficiency anemia in pregnant women |
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