Effects of Taurine–Magnesium Coordination Compound on Ionic Channels in Rat Ventricular Myocytes of Arrhythmia Induced by Ouabain

Taurine–magnesium coordination compound (TMCC) has anti-arrhythmic effects. The aim of the present study was to explore the targets of the anti-arrhythmic effect of TMCC and the electrophysiological effects of TMCC on ouabain-induced arrhythmias in rat ventricular myocytes. Sodium current (I Na), L-...

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Veröffentlicht in:	Biological trace element research 2012-06, Vol.147 (1-3), p.275-284
Hauptverfasser:	Zhao, Lin, Lou, Jianshi, Wu, Hong, Yin, Yongqiang, Kang, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Amiodarone - pharmacology Animals Anti-Arrhythmia Agents - pharmacology arrhythmia Biochemistry Biomedical and Life Sciences Biotechnology Calcium Calcium Channels, L-Type - physiology Cardiac arrhythmia cardiomyocytes Cardiotonic Agents - pharmacology Cells, Cultured Dietary minerals Dose-Response Relationship, Drug Female Heart Ventricles - cytology Inactivation Ion Channels - physiology Life Sciences Magnesium Magnesium - chemistry Magnesium - pharmacology Male Membrane Potentials - drug effects Myocytes, Cardiac - drug effects Myocytes, Cardiac - physiology Nutrition Oncology Organometallic Compounds - chemistry Organometallic Compounds - pharmacology ouabain Ouabain - pharmacology Patch-Clamp Techniques potassium Potassium Channels - physiology Rats Rats, Wistar Rodents Sodium Taurine - chemistry Taurine - pharmacology
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