Copper in Alzheimer's disease: too much or too little?

A considerable amount of literature has accrued examining the role of copper in the pathogenesis of Alzheimer's disease. Remarkably, there is in vitro and animal data to support both copper toxicity and copper deficiency as relevant mechanisms in Alzheimer's disease. These data have prompt...

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Veröffentlicht in:	Expert review of neurotherapeutics 2009-05, Vol.9 (5), p.631-637
Hauptverfasser:	Quinn, Joseph F, Crane, Susanne, Harris, Christopher, Wadsworth, Teri L
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - diet therapy Alzheimer Disease - drug therapy Alzheimer Disease - metabolism Alzheimer's disease animal model Animals Brain - metabolism chelation clinical trial Clinical Trials as Topic copper Copper - metabolism Copper - therapeutic use Hepatolenticular Degeneration - metabolism Humans oxidative damage Prevention Risk Factors
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