The hydroalcoholic extract of Cassia alata (Linn.) leaves and its major compound rhein exhibits antiallergic activity via mast cell stabilization and lipoxygenase inhibition

Leaves of Cassia alata (family: Caesalpiniaceae) are ethnomedically claimed as anti-asthmatic. In the current study we aimed to investigate the anti-allergic activities of hydro-methanolic extract of Cassia alata (Linn.) and its constituents rhein and kaempferol on triple antigen/sheep serum-induced...

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Veröffentlicht in:	Journal of ethnopharmacology 2012-05, Vol.141 (1), p.469-473
Hauptverfasser:	Singh, Baljinder, Nadkarni, Janhavi R., Vishwakarma, Ram A., Bharate, Sandip B., Nivsarkar, Manish, Anandjiwala, Sheetal
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic diseases Animals Anthraquinones - isolation & purification Anthraquinones - pharmacology Anti-Allergic Agents - isolation & purification Anti-Allergic Agents - pharmacology Antiallergic Antiallergics Asthma Caesalpiniaceae Cassia - chemistry Cassia alata Cell Degranulation - drug effects Chromatography, Thin Layer Degranulation Densitometry Enzymes HPTLC Kaempferol Kaempferols - pharmacology Leaves Lipoxygenase Lipoxygenase Inhibitors - isolation & purification Lipoxygenase Inhibitors - pharmacology Male Mast cells Mast Cells - drug effects Mast Cells - metabolism Methanol - chemistry Phytotherapy Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Leaves Plants, Medicinal Rats Rats, Sprague-Dawley Sheep Solvents - chemistry Standardization
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