The new truncated somatostatin receptor variant sst5TMD4 is associated to poor prognosis in breast cancer and increases malignancy in MCF-7 cells

Somatostatin receptors (sst1–5) are present in different types of tumors, where they inhibit key cellular processes such as proliferation and invasion. Although ssts are densely expressed in breast cancer, especially sst2, their role and therapeutic potential remain uncertain. Recently, we identifie...

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Veröffentlicht in:Oncogene 2012-04, Vol.31 (16), p.2049-2061
Hauptverfasser: Durán-Prado, M, Gahete, M D, Hergueta-Redondo, M, Martínez-Fuentes, A J, Córdoba-Chacón, J, Palacios, J, Gracia-Navarro, F, Moreno-Bueno, G, Malagón, M M, Luque, R M, Castaño, J P
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Sprache:eng
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