Risk of Serious Adverse Events Associated With Biologic and Nonbiologic Psoriasis Systemic Therapy: Patients Ineligible vs Eligible for Randomized Controlled Trials

OBJECTIVE To describe the use of systemic therapy for psoriasis (biologic and nonbiologic [classic] drugs) in patients not adequately represented in randomized controlled trials (RCTs) and the risk of serious adverse events (SAEs) in these patients. DESIGN A registry inception cohort was used. SETTI...

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Veröffentlicht in:	Archives of dermatology (1960) 2012-04, Vol.148 (4), p.463-470
Hauptverfasser:	Garcia-Doval, Ignacio, Carretero, Gregorio, Vanaclocha, Francisco, Ferrandiz, Carlos, Daudén, Esteban, Sánchez-Carazo, Jose-Luis, Alsina, Mercé, Herrera-Ceballos, Enrique, Gómez-García, Francisco-José, Ferrán, Marta, López-Estebaranz, Jose-Luis, Hernanz, Jose-Manuel, Belinchón-Romero, Isabel, Vilar-Alejo, Jaime, Rivera, Raquel, Carrascosa, Jose-Manuel, Carazo, Cristina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Age Factors Aged Anti-Inflammatory Agents - adverse effects Antibodies, Monoclonal - adverse effects Biological and medical sciences Biological Products - adverse effects Cancer Chronic infection Clinical trials Conferences Dermatology Drugs Elderly Female Geriatrics Hepatitis Hepatitis B Hepatitis C Historical account Human immunodeficiency virus Humans Immunosuppressive Agents - adverse effects infection Keratolytic Agents - adverse effects Kidney diseases Liver diseases Male Medical sciences Medical treatment Middle Aged Patient Selection Plaques Proportional Hazards Models Psoriasis Psoriasis - classification Psoriasis - drug therapy Psoriasis. Parapsoriasis. Lichen PUVA Therapy - adverse effects Randomized Controlled Trials as Topic Risk Assessment Risk factors Side effects Skin Skin cancer Spain
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