Association of streptomycin resistance mutations with level of drug resistance and Mycobacterium tuberculosis genotypes

OBJECTIVES: To determine 1) the relationship between specific streptomycin (SM) resistance mutations and the minimum inhibitory concentration (MIC), and 2) whether these mutations are preferentially associated with the Beijing genotype in Viet Nam.METHODS: A total of 131 consecutive Mycobacterium tu...

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Veröffentlicht in:	The international journal of tuberculosis and lung disease 2012-04, Vol.16 (4), p.527-531
Hauptverfasser:	Nhu, N. T. Q., Lan, N. T. N., Phuong, N. T. N., van V. Chau, N., Farrar, J., Caws, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antitubercular Agents - pharmacology Bacterial diseases Bacterial Typing Techniques - methods Beijing Genotype Biological and medical sciences Drug Resistance Drug Resistance, Bacterial - genetics Genotype Human bacterial diseases Humans Infectious diseases Medical sciences Microbial Sensitivity Tests Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Pharmacology. Drug treatments Pneumology Respiratory system : syndromes and miscellaneous diseases RNA, Bacterial Sequence Analysis, RNA - methods Streptomycin Streptomycin - pharmacology Tuberculosis Tuberculosis and atypical mycobacterial infections Tuberculosis, Multidrug-Resistant - diagnosis Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - microbiology Vietnam
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