Elevated serum angiotensin converting enzyme levels as a reflection of bone marrow renin–angiotensin system activation in multiple myeloma

Introduction: Angiotensin converting enzyme (ACE) is a circulating enzyme that participates in the body’s renin–angiotensin system (RAS) and is localized on the endothelial cell surface in the lung and other vascular beds. It catalyses the conversion of decapeptide angiotensin I to octapeptide angio...

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