Typical and atypical antipsychotic drugs increase extracellular histamine levels in the rat medial prefrontal cortex: contribution of histamine h(1) receptor blockade

Atypical antipsychotics such as clozapine and olanzapine have been shown to enhance histamine turnover and this effect has been hypothesized to contribute to their improved therapeutic profile compared to typical antipsychotics. In the present study, we examined the effects of antipsychotic drugs on...

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Veröffentlicht in:Frontiers in psychiatry 2012, Vol.3, p.49-49
Hauptverfasser: Fell, Matthew J, Katner, Jason S, Rasmussen, Kurt, Nikolayev, Alexander, Kuo, Ming-Shang, Nelson, David L G, Perry, Kenneth W, Svensson, Kjell A
Format: Artikel
Sprache:eng
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