68Ga DOTANOC PET/CT Detects Medullary Thyroid Cancer Relapse at Bone Level
ABSTRACTA patient with a history of radical thyroidectomy for medullary thyroid carcinoma (MTC) was studied by Ga [DOTA,1-Nal3]octreotide PET/CT for suspected relapse. PET/CT documented a focal area of somatostatin receptors expression at bone level. Although Ga DOTA-peptides PET has been successful...
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Veröffentlicht in: | Clinical nuclear medicine 2012-06, Vol.37 (6), p.591-592 |
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creator | Nicolini, Silvia Valentina, Ambrosini Lorenzo, Fantini Stefano, Fanti |
description | ABSTRACTA patient with a history of radical thyroidectomy for medullary thyroid carcinoma (MTC) was studied by Ga [DOTA,1-Nal3]octreotide PET/CT for suspected relapse. PET/CT documented a focal area of somatostatin receptors expression at bone level. Although Ga DOTA-peptides PET has been successfully used for the detection of neuroendocrine tumors, its role in MTC patients is still under evaluation. In fact, although deriving from the neural crest, MTC cells may show a variable expression of somatostatin receptors. This case shows that PET/CT with DOTANOC may be a useful complementary imaging modality in patients with well-differentiated MTC. |
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subjects | Bone Neoplasms - secondary Carcinoma, Neuroendocrine Female Humans Middle Aged Multimodal Imaging Organometallic Compounds Positron-Emission Tomography Recurrence Thyroid Neoplasms - diagnostic imaging Thyroid Neoplasms - pathology Tomography, X-Ray Computed |
title | 68Ga DOTANOC PET/CT Detects Medullary Thyroid Cancer Relapse at Bone Level |
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