68Ga DOTANOC PET/CT Detects Medullary Thyroid Cancer Relapse at Bone Level

ABSTRACTA patient with a history of radical thyroidectomy for medullary thyroid carcinoma (MTC) was studied by Ga [DOTA,1-Nal3]octreotide PET/CT for suspected relapse. PET/CT documented a focal area of somatostatin receptors expression at bone level. Although Ga DOTA-peptides PET has been successful...

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Veröffentlicht in:Clinical nuclear medicine 2012-06, Vol.37 (6), p.591-592
Hauptverfasser: Nicolini, Silvia, Valentina, Ambrosini, Lorenzo, Fantini, Stefano, Fanti
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container_end_page 592
container_issue 6
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container_title Clinical nuclear medicine
container_volume 37
creator Nicolini, Silvia
Valentina, Ambrosini
Lorenzo, Fantini
Stefano, Fanti
description ABSTRACTA patient with a history of radical thyroidectomy for medullary thyroid carcinoma (MTC) was studied by Ga [DOTA,1-Nal3]octreotide PET/CT for suspected relapse. PET/CT documented a focal area of somatostatin receptors expression at bone level. Although Ga DOTA-peptides PET has been successfully used for the detection of neuroendocrine tumors, its role in MTC patients is still under evaluation. In fact, although deriving from the neural crest, MTC cells may show a variable expression of somatostatin receptors. This case shows that PET/CT with DOTANOC may be a useful complementary imaging modality in patients with well-differentiated MTC.
doi_str_mv 10.1097/RLU.0b013e31824c5eab
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subjects Bone Neoplasms - secondary
Carcinoma, Neuroendocrine
Female
Humans
Middle Aged
Multimodal Imaging
Organometallic Compounds
Positron-Emission Tomography
Recurrence
Thyroid Neoplasms - diagnostic imaging
Thyroid Neoplasms - pathology
Tomography, X-Ray Computed
title 68Ga DOTANOC PET/CT Detects Medullary Thyroid Cancer Relapse at Bone Level
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