TLR2 may influence the behavior of the malignant clone in B-CLL

B-cell receptor (BCR) and Toll-like receptor (TLR) stimulation and integration with signals from the pathogen or immune cells and their products determine the B-cell antibody response. Low expression of BCR is the hallmark of B lymphocytes in CLL, however little is known about the expression and fun...

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Veröffentlicht in:	Blood cells, molecules, & diseases molecules, & diseases, 2012-06, Vol.49 (1), p.32-40
Hauptverfasser:	Antosz, Halina, Sajewicz, Joanna, Marzec-Kotarska, Barbara, Dmoszyńska, Anna, Baszak, Jacek, Jargiełło-Baszak, Małgorzata
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over B-CLL Female Gene Expression Regulation, Leukemic - drug effects Gene Expression Regulation, Leukemic - immunology Humans IL-6 Interleukin-6 - biosynthesis Interleukin-6 - immunology Leukemia, Lymphocytic, Chronic, B-Cell - immunology Leukemia, Lymphocytic, Chronic, B-Cell - metabolism Lipopolysaccharides - pharmacology Male Middle Aged mIL-6Rα Receptors, Antigen, B-Cell - biosynthesis Receptors, Antigen, B-Cell - immunology Staphylococcus aureus - immunology TLR2 TLR4 Toll-Like Receptor 2 - biosynthesis Toll-Like Receptor 2 - immunology Toll-Like Receptor 4 - biosynthesis Toll-Like Receptor 4 - immunology
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