Prognostic Value of Preoperative Metabolic Tumor Volume and Total Lesion Glycolysis in Patients with Epithelial Ovarian Cancer
Purpose Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are measures of metabolic activity of tumors determined by fluorine-18 fluorodeoxyglucose ([ 18 F]FDG) uptake on PET/CT images. The purpose of this study was to investigate the relationship between functional tumor parameters (MT...
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| Veröffentlicht in: | Annals of surgical oncology 2012-06, Vol.19 (6), p.1966-1972 |
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| container_issue | 6 |
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| container_title | Annals of surgical oncology |
| container_volume | 19 |
| creator | Chung, Hyun Hoon Kwon, Hyun Woo Kang, Keon Wook Park, Noh-Hyun Song, Yong-Sang Chung, June-Key Kang, Soon-Beom Kim, Jae Weon |
| description | Purpose
Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are measures of metabolic activity of tumors determined by fluorine-18 fluorodeoxyglucose ([
18
F]FDG) uptake on PET/CT images. The purpose of this study was to investigate the relationship between functional tumor parameters (MTV and TLG) and clinical outcomes in patients with epithelial ovarian cancer (EOC).
Methods
Fifty-five patients with EOC who had undergone [
18
F]FDG PET/CT before surgical staging were included in this retrospectively study. For each patient, we determined the highest (SUV
max
and SUV
avg
), the cumulative TLG, and the sum of all MTV, and compared their predictive value of recurrence and the effects of pretreatment functional tumor activity on progression-free interval (PFI).
Results
The median duration of PFI was 11 (range 3–43) months, and 20 patients (36.4%) experienced recurrence. Poor outcome was associated with higher values for both the MTV (
P
= 0.022, hazard ratio 5.571, 95% confidence interval 1.279–24.272) and the TLG (
P
= 0.037, hazard ratio 2.967, 95% confidence interval 1.065–8.265). The Kaplan–Meier survival graphs showed a significant difference in PFI between the groups categorized by MTV and TLG, respectively (
P
=
0.01 for MTV,
P
=
0.0287 for TLG, log rank test).
Conclusions
Pretreatment metabolic parameters such as MTV and TLG showed statistically significant association with recurrence in patients with EOC. These values can be useful quantitative criteria for disease prognostication in patients with EOC before treatment. |
| doi_str_mv | 10.1245/s10434-011-2153-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1015247872</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1015247872</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-1619d2713482a0fe99ac9645e2a310c68a65d89d2664e2087b4b36dad82286c03</originalsourceid><addsrcrecordid>eNp1kU9vEzEQxS0EoqXlA3BBlrhwWfD_9R5RVApSUHNIe1053klx5bWDvVuaC5-daVMQQuplZqT5vTeWHyFvOPvAhdIfK2dKqoZx3giuZXP3jBxjV40ylj_HmRnbdMLoI_Kq1hvGeCuZfkmOhEB9q9tj8mtV8nXKdQqeXrk4A81buiqQd1DcFG6BfoPJbXLE_Xoec6FXOc4jUJcGus6Ti3QJNeREz-Pe57ivodKQ6ArFkKZKf4bpOz3bYYUYkL64dSW4RBcueSin5MXWxQqvH_sJufx8tl58aZYX518Xn5aNl62YGm54N4iWS2WFY1voOuc7ozQIJznzxjqjB4uIMQoEs-1GbaQZ3GCFsMYzeULeH3x3Jf-YoU79GKqHGF2CPNeeM67xR2wrEH33H3qT55LwdQ8U40K2Gil-oHzJtRbY9rsSRlf2CPX34fSHcHoMp78Pp79DzdtH53kzwvBX8ScNBMQBqLhK11D-Pf2U628bZ5pH</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1015012375</pqid></control><display><type>article</type><title>Prognostic Value of Preoperative Metabolic Tumor Volume and Total Lesion Glycolysis in Patients with Epithelial Ovarian Cancer</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Chung, Hyun Hoon ; Kwon, Hyun Woo ; Kang, Keon Wook ; Park, Noh-Hyun ; Song, Yong-Sang ; Chung, June-Key ; Kang, Soon-Beom ; Kim, Jae Weon</creator><creatorcontrib>Chung, Hyun Hoon ; Kwon, Hyun Woo ; Kang, Keon Wook ; Park, Noh-Hyun ; Song, Yong-Sang ; Chung, June-Key ; Kang, Soon-Beom ; Kim, Jae Weon</creatorcontrib><description>Purpose
Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are measures of metabolic activity of tumors determined by fluorine-18 fluorodeoxyglucose ([
18
F]FDG) uptake on PET/CT images. The purpose of this study was to investigate the relationship between functional tumor parameters (MTV and TLG) and clinical outcomes in patients with epithelial ovarian cancer (EOC).
Methods
Fifty-five patients with EOC who had undergone [
18
F]FDG PET/CT before surgical staging were included in this retrospectively study. For each patient, we determined the highest (SUV
max
and SUV
avg
), the cumulative TLG, and the sum of all MTV, and compared their predictive value of recurrence and the effects of pretreatment functional tumor activity on progression-free interval (PFI).
Results
The median duration of PFI was 11 (range 3–43) months, and 20 patients (36.4%) experienced recurrence. Poor outcome was associated with higher values for both the MTV (
P
= 0.022, hazard ratio 5.571, 95% confidence interval 1.279–24.272) and the TLG (
P
= 0.037, hazard ratio 2.967, 95% confidence interval 1.065–8.265). The Kaplan–Meier survival graphs showed a significant difference in PFI between the groups categorized by MTV and TLG, respectively (
P
=
0.01 for MTV,
P
=
0.0287 for TLG, log rank test).
Conclusions
Pretreatment metabolic parameters such as MTV and TLG showed statistically significant association with recurrence in patients with EOC. These values can be useful quantitative criteria for disease prognostication in patients with EOC before treatment.</description><identifier>ISSN: 1068-9265</identifier><identifier>EISSN: 1534-4681</identifier><identifier>DOI: 10.1245/s10434-011-2153-x</identifier><identifier>PMID: 22124757</identifier><language>eng</language><publisher>New York: Springer-Verlag</publisher><subject>Adenocarcinoma, Clear Cell - diagnosis ; Adenocarcinoma, Clear Cell - mortality ; Adenocarcinoma, Clear Cell - surgery ; Adenocarcinoma, Mucinous - diagnosis ; Adenocarcinoma, Mucinous - mortality ; Adenocarcinoma, Mucinous - surgery ; Adult ; Aged ; Aged, 80 and over ; Cystadenocarcinoma, Serous - diagnosis ; Cystadenocarcinoma, Serous - mortality ; Cystadenocarcinoma, Serous - surgery ; Endometrial Neoplasms - diagnosis ; Endometrial Neoplasms - mortality ; Endometrial Neoplasms - surgery ; Female ; Fluorodeoxyglucose F18 ; Follow-Up Studies ; Glycolysis ; Gynecologic Oncology ; Humans ; Medicine ; Medicine & Public Health ; Middle Aged ; Multimodal Imaging ; Neoplasm Grading ; Neoplasm Recurrence, Local - diagnosis ; Neoplasm Recurrence, Local - mortality ; Neoplasm Recurrence, Local - surgery ; Neoplasm Staging ; Oncology ; Ovarian cancer ; Ovarian Neoplasms - diagnosis ; Ovarian Neoplasms - mortality ; Ovarian Neoplasms - surgery ; Positron-Emission Tomography ; Prognosis ; Radiopharmaceuticals ; Retrospective Studies ; Surgery ; Surgical Oncology ; Survival Rate ; Tomography, X-Ray Computed</subject><ispartof>Annals of surgical oncology, 2012-06, Vol.19 (6), p.1966-1972</ispartof><rights>Society of Surgical Oncology 2011</rights><rights>Society of Surgical Oncology 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-1619d2713482a0fe99ac9645e2a310c68a65d89d2664e2087b4b36dad82286c03</citedby><cites>FETCH-LOGICAL-c372t-1619d2713482a0fe99ac9645e2a310c68a65d89d2664e2087b4b36dad82286c03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1245/s10434-011-2153-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1245/s10434-011-2153-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22124757$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chung, Hyun Hoon</creatorcontrib><creatorcontrib>Kwon, Hyun Woo</creatorcontrib><creatorcontrib>Kang, Keon Wook</creatorcontrib><creatorcontrib>Park, Noh-Hyun</creatorcontrib><creatorcontrib>Song, Yong-Sang</creatorcontrib><creatorcontrib>Chung, June-Key</creatorcontrib><creatorcontrib>Kang, Soon-Beom</creatorcontrib><creatorcontrib>Kim, Jae Weon</creatorcontrib><title>Prognostic Value of Preoperative Metabolic Tumor Volume and Total Lesion Glycolysis in Patients with Epithelial Ovarian Cancer</title><title>Annals of surgical oncology</title><addtitle>Ann Surg Oncol</addtitle><addtitle>Ann Surg Oncol</addtitle><description>Purpose
Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are measures of metabolic activity of tumors determined by fluorine-18 fluorodeoxyglucose ([
18
F]FDG) uptake on PET/CT images. The purpose of this study was to investigate the relationship between functional tumor parameters (MTV and TLG) and clinical outcomes in patients with epithelial ovarian cancer (EOC).
Methods
Fifty-five patients with EOC who had undergone [
18
F]FDG PET/CT before surgical staging were included in this retrospectively study. For each patient, we determined the highest (SUV
max
and SUV
avg
), the cumulative TLG, and the sum of all MTV, and compared their predictive value of recurrence and the effects of pretreatment functional tumor activity on progression-free interval (PFI).
Results
The median duration of PFI was 11 (range 3–43) months, and 20 patients (36.4%) experienced recurrence. Poor outcome was associated with higher values for both the MTV (
P
= 0.022, hazard ratio 5.571, 95% confidence interval 1.279–24.272) and the TLG (
P
= 0.037, hazard ratio 2.967, 95% confidence interval 1.065–8.265). The Kaplan–Meier survival graphs showed a significant difference in PFI between the groups categorized by MTV and TLG, respectively (
P
=
0.01 for MTV,
P
=
0.0287 for TLG, log rank test).
Conclusions
Pretreatment metabolic parameters such as MTV and TLG showed statistically significant association with recurrence in patients with EOC. These values can be useful quantitative criteria for disease prognostication in patients with EOC before treatment.</description><subject>Adenocarcinoma, Clear Cell - diagnosis</subject><subject>Adenocarcinoma, Clear Cell - mortality</subject><subject>Adenocarcinoma, Clear Cell - surgery</subject><subject>Adenocarcinoma, Mucinous - diagnosis</subject><subject>Adenocarcinoma, Mucinous - mortality</subject><subject>Adenocarcinoma, Mucinous - surgery</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cystadenocarcinoma, Serous - diagnosis</subject><subject>Cystadenocarcinoma, Serous - mortality</subject><subject>Cystadenocarcinoma, Serous - surgery</subject><subject>Endometrial Neoplasms - diagnosis</subject><subject>Endometrial Neoplasms - mortality</subject><subject>Endometrial Neoplasms - surgery</subject><subject>Female</subject><subject>Fluorodeoxyglucose F18</subject><subject>Follow-Up Studies</subject><subject>Glycolysis</subject><subject>Gynecologic Oncology</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Multimodal Imaging</subject><subject>Neoplasm Grading</subject><subject>Neoplasm Recurrence, Local - diagnosis</subject><subject>Neoplasm Recurrence, Local - mortality</subject><subject>Neoplasm Recurrence, Local - surgery</subject><subject>Neoplasm Staging</subject><subject>Oncology</subject><subject>Ovarian cancer</subject><subject>Ovarian Neoplasms - diagnosis</subject><subject>Ovarian Neoplasms - mortality</subject><subject>Ovarian Neoplasms - surgery</subject><subject>Positron-Emission Tomography</subject><subject>Prognosis</subject><subject>Radiopharmaceuticals</subject><subject>Retrospective Studies</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Survival Rate</subject><subject>Tomography, X-Ray Computed</subject><issn>1068-9265</issn><issn>1534-4681</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU9vEzEQxS0EoqXlA3BBlrhwWfD_9R5RVApSUHNIe1053klx5bWDvVuaC5-daVMQQuplZqT5vTeWHyFvOPvAhdIfK2dKqoZx3giuZXP3jBxjV40ylj_HmRnbdMLoI_Kq1hvGeCuZfkmOhEB9q9tj8mtV8nXKdQqeXrk4A81buiqQd1DcFG6BfoPJbXLE_Xoec6FXOc4jUJcGus6Ti3QJNeREz-Pe57ivodKQ6ArFkKZKf4bpOz3bYYUYkL64dSW4RBcueSin5MXWxQqvH_sJufx8tl58aZYX518Xn5aNl62YGm54N4iWS2WFY1voOuc7ozQIJznzxjqjB4uIMQoEs-1GbaQZ3GCFsMYzeULeH3x3Jf-YoU79GKqHGF2CPNeeM67xR2wrEH33H3qT55LwdQ8U40K2Gil-oHzJtRbY9rsSRlf2CPX34fSHcHoMp78Pp79DzdtH53kzwvBX8ScNBMQBqLhK11D-Pf2U628bZ5pH</recordid><startdate>20120601</startdate><enddate>20120601</enddate><creator>Chung, Hyun Hoon</creator><creator>Kwon, Hyun Woo</creator><creator>Kang, Keon Wook</creator><creator>Park, Noh-Hyun</creator><creator>Song, Yong-Sang</creator><creator>Chung, June-Key</creator><creator>Kang, Soon-Beom</creator><creator>Kim, Jae Weon</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20120601</creationdate><title>Prognostic Value of Preoperative Metabolic Tumor Volume and Total Lesion Glycolysis in Patients with Epithelial Ovarian Cancer</title><author>Chung, Hyun Hoon ; Kwon, Hyun Woo ; Kang, Keon Wook ; Park, Noh-Hyun ; Song, Yong-Sang ; Chung, June-Key ; Kang, Soon-Beom ; Kim, Jae Weon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-1619d2713482a0fe99ac9645e2a310c68a65d89d2664e2087b4b36dad82286c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adenocarcinoma, Clear Cell - diagnosis</topic><topic>Adenocarcinoma, Clear Cell - mortality</topic><topic>Adenocarcinoma, Clear Cell - surgery</topic><topic>Adenocarcinoma, Mucinous - diagnosis</topic><topic>Adenocarcinoma, Mucinous - mortality</topic><topic>Adenocarcinoma, Mucinous - surgery</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cystadenocarcinoma, Serous - diagnosis</topic><topic>Cystadenocarcinoma, Serous - mortality</topic><topic>Cystadenocarcinoma, Serous - surgery</topic><topic>Endometrial Neoplasms - diagnosis</topic><topic>Endometrial Neoplasms - mortality</topic><topic>Endometrial Neoplasms - surgery</topic><topic>Female</topic><topic>Fluorodeoxyglucose F18</topic><topic>Follow-Up Studies</topic><topic>Glycolysis</topic><topic>Gynecologic Oncology</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Multimodal Imaging</topic><topic>Neoplasm Grading</topic><topic>Neoplasm Recurrence, Local - diagnosis</topic><topic>Neoplasm Recurrence, Local - mortality</topic><topic>Neoplasm Recurrence, Local - surgery</topic><topic>Neoplasm Staging</topic><topic>Oncology</topic><topic>Ovarian cancer</topic><topic>Ovarian Neoplasms - diagnosis</topic><topic>Ovarian Neoplasms - mortality</topic><topic>Ovarian Neoplasms - surgery</topic><topic>Positron-Emission Tomography</topic><topic>Prognosis</topic><topic>Radiopharmaceuticals</topic><topic>Retrospective Studies</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Survival Rate</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chung, Hyun Hoon</creatorcontrib><creatorcontrib>Kwon, Hyun Woo</creatorcontrib><creatorcontrib>Kang, Keon Wook</creatorcontrib><creatorcontrib>Park, Noh-Hyun</creatorcontrib><creatorcontrib>Song, Yong-Sang</creatorcontrib><creatorcontrib>Chung, June-Key</creatorcontrib><creatorcontrib>Kang, Soon-Beom</creatorcontrib><creatorcontrib>Kim, Jae Weon</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chung, Hyun Hoon</au><au>Kwon, Hyun Woo</au><au>Kang, Keon Wook</au><au>Park, Noh-Hyun</au><au>Song, Yong-Sang</au><au>Chung, June-Key</au><au>Kang, Soon-Beom</au><au>Kim, Jae Weon</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic Value of Preoperative Metabolic Tumor Volume and Total Lesion Glycolysis in Patients with Epithelial Ovarian Cancer</atitle><jtitle>Annals of surgical oncology</jtitle><stitle>Ann Surg Oncol</stitle><addtitle>Ann Surg Oncol</addtitle><date>2012-06-01</date><risdate>2012</risdate><volume>19</volume><issue>6</issue><spage>1966</spage><epage>1972</epage><pages>1966-1972</pages><issn>1068-9265</issn><eissn>1534-4681</eissn><abstract>Purpose
Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are measures of metabolic activity of tumors determined by fluorine-18 fluorodeoxyglucose ([
18
F]FDG) uptake on PET/CT images. The purpose of this study was to investigate the relationship between functional tumor parameters (MTV and TLG) and clinical outcomes in patients with epithelial ovarian cancer (EOC).
Methods
Fifty-five patients with EOC who had undergone [
18
F]FDG PET/CT before surgical staging were included in this retrospectively study. For each patient, we determined the highest (SUV
max
and SUV
avg
), the cumulative TLG, and the sum of all MTV, and compared their predictive value of recurrence and the effects of pretreatment functional tumor activity on progression-free interval (PFI).
Results
The median duration of PFI was 11 (range 3–43) months, and 20 patients (36.4%) experienced recurrence. Poor outcome was associated with higher values for both the MTV (
P
= 0.022, hazard ratio 5.571, 95% confidence interval 1.279–24.272) and the TLG (
P
= 0.037, hazard ratio 2.967, 95% confidence interval 1.065–8.265). The Kaplan–Meier survival graphs showed a significant difference in PFI between the groups categorized by MTV and TLG, respectively (
P
=
0.01 for MTV,
P
=
0.0287 for TLG, log rank test).
Conclusions
Pretreatment metabolic parameters such as MTV and TLG showed statistically significant association with recurrence in patients with EOC. These values can be useful quantitative criteria for disease prognostication in patients with EOC before treatment.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>22124757</pmid><doi>10.1245/s10434-011-2153-x</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1068-9265 |
| ispartof | Annals of surgical oncology, 2012-06, Vol.19 (6), p.1966-1972 |
| issn | 1068-9265 1534-4681 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adenocarcinoma, Clear Cell - diagnosis Adenocarcinoma, Clear Cell - mortality Adenocarcinoma, Clear Cell - surgery Adenocarcinoma, Mucinous - diagnosis Adenocarcinoma, Mucinous - mortality Adenocarcinoma, Mucinous - surgery Adult Aged Aged, 80 and over Cystadenocarcinoma, Serous - diagnosis Cystadenocarcinoma, Serous - mortality Cystadenocarcinoma, Serous - surgery Endometrial Neoplasms - diagnosis Endometrial Neoplasms - mortality Endometrial Neoplasms - surgery Female Fluorodeoxyglucose F18 Follow-Up Studies Glycolysis Gynecologic Oncology Humans Medicine Medicine & Public Health Middle Aged Multimodal Imaging Neoplasm Grading Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - surgery Neoplasm Staging Oncology Ovarian cancer Ovarian Neoplasms - diagnosis Ovarian Neoplasms - mortality Ovarian Neoplasms - surgery Positron-Emission Tomography Prognosis Radiopharmaceuticals Retrospective Studies Surgery Surgical Oncology Survival Rate Tomography, X-Ray Computed |
| title | Prognostic Value of Preoperative Metabolic Tumor Volume and Total Lesion Glycolysis in Patients with Epithelial Ovarian Cancer |
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