Significance of Ki-67 and p53 immunoexpression in the differential diagnosis of oral necrotizing sialometaplasia and squamous cell carcinoma

Abstract Necrotizing sialometaplasia (NS) is a benign condition that usually involves the hard palate and can be mistaken for invasive squamous cell carcinoma (SCC). In this study, we have demonstrated that p53 and Ki-67 staining may assist in the differential diagnosis of NS from SCC. Thirteen case...

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Veröffentlicht in:	Annals of diagnostic pathology 2012-06, Vol.16 (3), p.171-176
Hauptverfasser:	Dadfarnia, Tahereh, MD, Mohammed, Bassim S., MD, Eltorky, Mahmoud A., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biomarkers, Tumor - analysis Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - metabolism Child Diagnosis, Differential Female Humans Immunohistochemistry Infant Ki-67 Ki-67 Antigen - biosynthesis Male Middle Aged Mouth Neoplasms - diagnosis Mouth Neoplasms - metabolism Necrotizing sialometaplasia p53 Pathology Sialometaplasia, Necrotizing - diagnosis Sialometaplasia, Necrotizing - metabolism Squamous cell carcinoma Tumor Suppressor Protein p53 - biosynthesis
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