Scorpio and Scolopendra attenuate inflammation and articular damage in rats with collagen-induced arthritis

Rheumatoid arthritis (RA) is a treatment-refractory chronic autoimmune disease. The therapeutic goals of RA are remission of clinical symptoms and increase functional ability by restrain inflammatory and disordered immune response. Scorpio and Scolopendra (SS) in Chinese pharmacopoeia are usually us...

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Veröffentlicht in:	Journal of ethnopharmacology 2012-06, Vol.141 (2), p.603-607
Hauptverfasser:	Liu, Duan-Yong, Zhao, Hai-Mei, Cheng, Shao-Min, Rao, Yi, Huang, Xiao-Ying, Zuo, Zhi-Qin, Lei, Meng, Guan, Yong-Mei, Liu, Hong-Ning, Lu, Ai-Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Antibodies - blood Arthritis, Experimental - drug therapy Arthritis, Experimental - immunology Arthritis, Experimental - pathology Collagen Type II - immunology Collagen-induced arthritis Diterpene Alkaloids Dose-Response Relationship, Drug Drugs, Chinese Herbal - pharmacology Female Inflammation Mediators - metabolism Interleukin-10 - metabolism Interleukin-1beta - metabolism Interleukin-4 - metabolism Joints - drug effects Joints - immunology Joints - pathology Medicine, Chinese Traditional Plants, Medicinal Powders Rats Rats, Wistar Scolopendra Scorpio T-Lymphocytes - drug effects T-Lymphocytes - immunology Therapeutic effect Time Factors Tumor Necrosis Factor-alpha - metabolism
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