Increased Gut Microbial Translocation in HIV-infected Children Persists in Virologic Responders and Virologic Failures After Antiretroviral Therapy

BACKGROUND:Gut microbial translocation (MT) is considered a major cause of immune activation (IA) and failure of immune reconstitution in HIV infection. This study investigated the relationship of virus replication, IA, CD4 counts and MT in HIV-infected children. METHODS:Lipopolysaccharide, bacteria...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Pediatric infectious disease journal 2012-06, Vol.31 (6), p.583-591
Hauptverfasser:	Pilakka-Kanthikeel, Sudheesh, Huang, Sharon, Fenton, Terry, Borkowsky, William, Cunningham, Coleen K, Pahwa, Savita
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anti-HIV Agents - administration & dosage Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral Therapy, Highly Active - methods Antiviral agents Bacteremia - epidemiology Bacterial Translocation Biological and medical sciences CD4 Lymphocyte Count Child Child, Preschool DNA, Bacterial - blood DNA, Ribosomal - blood Female HIV Infections - complications HIV Infections - drug therapy Human viral diseases Humans Immune Reconstitution Inflammatory Syndrome - epidemiology Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Lipopolysaccharides - blood Male Medical sciences Pharmacology. Drug treatments Prospective Studies RNA, Ribosomal, 16S - genetics Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!