From the Field of Play to the Field of Combat: A Review of the Pharmacological Management of Concussion
Traditionally, the medical management of concussion has involved close observation and physical and cognitive rest. Most postconcussive symptoms resolve spontaneously and require only conservative treatment. However, some patients have prolonged recoveries and may benefit from treatment with medicat...
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| Veröffentlicht in: | Neurosurgery 2012-06, Vol.70 (6), p.1520-1533 |
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| creator | PETRAGLIA, Anthony L MAROON, Joseph C BAILES, Julian E |
| description | Traditionally, the medical management of concussion has involved close observation and physical and cognitive rest. Most postconcussive symptoms resolve spontaneously and require only conservative treatment. However, some patients have prolonged recoveries and may benefit from treatment with medications. Some naturally occurring compounds demonstrate multimechanistic neuroprotective properties and may be potential treatment considerations. For the most part, however, current treatments are symptom based for those with persistent postconcussive symptoms. The evidence supporting the various pharmacologic treatments in concussion is equivocal. The choice of which medication to use for a patient depends on the symptom characteristics, and each decision should be made on an individual-case basis. There is a need for well-designed trials investigating the efficacy of various medical therapies. |
| doi_str_mv | 10.1227/NEU.0b013e31824cebe8 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0148-396X |
| ispartof | Neurosurgery, 2012-06, Vol.70 (6), p.1520-1533 |
| issn | 0148-396X 1524-4040 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Athletic Injuries - complications Biological and medical sciences Brain Concussion - drug therapy Brain Concussion - etiology Brain Concussion - physiopathology Concussion Humans Medical sciences Neuroprotective Agents - therapeutic use Neurosurgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Warfare |
| title | From the Field of Play to the Field of Combat: A Review of the Pharmacological Management of Concussion |
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