Total Survivin and acetylated Survivin correlate with distinct molecular subtypes of breast cancer

Summary Global gene expression profiling studies led to the recent classification of breast cancer into 4 distinct molecular subtypes including luminal, human epidermal growth factor receptor 2 enriched, basal like, and unclassified. Here, we used immunohistochemistry to evaluate expression of the a...

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Veröffentlicht in:	Human pathology 2012-06, Vol.43 (6), p.865-873
Hauptverfasser:	Yakirevich, Evgeny, MD, DSc, Samkari, Ayman, MD, Holloway, Michael P., PhD, Lu, Shaolei, MD, PhD, Singh, Kamaljeet, MD, Yu, Jovian, Fenton, Mary Anne, MD, Altura, Rachel A., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Apoptosis Basal breast cancer Biological and medical sciences Biomarkers, Tumor - analysis Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - pathology Female Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Inhibitor of Apoptosis Proteins - biosynthesis Inhibitor of Apoptosis Proteins - genetics Investigative techniques, diagnostic techniques (general aspects) Kaplan-Meier Estimate Mammary gland diseases Medical sciences Middle Aged Neoplasm Staging Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prognosis Proportional Hazards Models Proteins Survivin Tissue Array Analysis Triple-negative breast cancer Tumors
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