NO CONSISTENT EVIDENCE FOR ASSOCIATION BETWEEN mtDNA VARIANTS AND ALZHEIMER DISEASE

Objective: Although several studies have described an association between Alzheimer disease (AD) and genetic variation of mitochondrial DNA (mtDNA), each has implicated different mtDNA variants, so the role of mtDNA in the etiology of AD remains uncertain. Methods: We tested 138 mtDNA variants for a...

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Veröffentlicht in:	Neurology 2012-04, Vol.78 (15), p.1038-1042
Hauptverfasser:	Hudson, G, Sims, R, Harold, D, Chapman, J, Hollingworth, P, Gerrish, A, Russo, G, Hamshere, M, Moskvina, V, Jones, N, Thomas, C, Stretton, A, Holmans, P A, O'Donovan, M C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Data processing Etiology Genetic diversity Geriatrics Mitochondrial DNA Neurodegenerative diseases Nitric oxide Quality control Reviews
Online-Zugang:	Volltext
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