GluA and GluN receptors regulate the surface density of GluN receptor subunits in cultured neocortical interneurons

J. Neurochem. (2012) 121, 597–606. In cultured rat neocortical interneurons, we have studied the effect of long‐term application of NMDA or AMPA on the surface density of the NMDA (GluN) receptor subunits GluN1 and GluN2B. Stimulation of Ca2+‐permeable AMPA (GluA) receptors located on the interneuro...

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Veröffentlicht in:	Journal of neurochemistry 2012-05, Vol.121 (4), p.597-606
Hauptverfasser:	Meyer, Dieter K., Lindemeyer, A. Kerstin, Wilmes, Thomas, Sobottka, Helga, Nörenberg, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms alpha -Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology Animals Biological and medical sciences Biotinylation Calcium Signaling - drug effects Cell receptors Cell structures and functions Cells, Cultured Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Cortex down-regulation Down-Regulation - drug effects Down-Regulation - physiology Electrophysiological Phenomena Endocytosis Excitatory Amino Acid Agonists - pharmacology Fundamental and applied biological sciences. Psychology GluN response Glutamic acid receptors Glutamic acid receptors (ionotropic) Immunohistochemistry Interneurons Interneurons - drug effects Interneurons - physiology long-term changes Molecular and cellular biology Monoamines receptors (catecholamine, serotonine, histamine, acetylcholine) N-Methyl-D-aspartic acid N-Methyl-D-aspartic acid receptors N-Methylaspartate - pharmacology Neocortex - cytology Neocortex - drug effects Neocortex - physiology Nerve Net - cytology Nerve Net - physiology Neurons NMDA Patch-Clamp Techniques Rats Rats, Wistar Receptor density Receptors, AMPA - drug effects Receptors, AMPA - physiology Receptors, Cell Surface - drug effects Receptors, Cell Surface - physiology Receptors, N-Methyl-D-Aspartate - drug effects Receptors, N-Methyl-D-Aspartate - physiology Rodents Surface tension Tetrodotoxin - pharmacology Vertebrates: nervous system and sense organs
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