Different safety profiles of risperidone and paliperidone extended-release: a double-blind, placebo-controlled trial with healthy volunteers

Objective The present study investigated subjective experiences related to secondary negative symptoms and cognitive performance in healthy volunteers in response to the repeated administration of paliperidone extended‐release (ER) and risperidone in a double‐blind, placebo‐controlled trial. Methods...

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Veröffentlicht in:	Human psychopharmacology 2012-05, Vol.27 (3), p.305-314
Hauptverfasser:	Yoon, Kil-Sang, Park, Tae-Won, Yang, Jong-Chul, Kim, Min-Gul, Oh, Keun-Young, Park, Myung-Sook, Chung, Young-Chul
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance Antipsychotic Agents - administration & dosage Chi-Square Distribution Cognition - drug effects cognitive function Double-Blind Method Drug Administration Schedule Drug Delivery Systems Female Humans Isoxazoles - administration & dosage Male negative symptoms Neuropsychological Tests Pain Measurement paliperidone Paliperidone Palmitate Psychiatric Status Rating Scales Pyrimidines - administration & dosage Risperidone - administration & dosage schizophrenia Substance-Related Disorders - diagnosis Substance-Related Disorders - etiology Time Factors
Online-Zugang:	Volltext
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