Lenalidomide after Stem-Cell Transplantation for Multiple Myeloma

In patients who had undergone stem-cell transplantation, lenalidomide maintenance therapy improved progression-free and overall survival, though at the expense of some increased hematologic toxicity and second malignant tumors. A goal of therapy for multiple myeloma, to induce complete remission and...

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Veröffentlicht in:	The New England journal of medicine 2012-05, Vol.366 (19), p.1770-1781
Hauptverfasser:	McCarthy, Philip L, Owzar, Kouros, Hofmeister, Craig C, Hurd, David D, Hassoun, Hani, Richardson, Paul G, Giralt, Sergio, Stadtmauer, Edward A, Weisdorf, Daniel J, Vij, Ravi, Moreb, Jan S, Callander, Natalie Scott, Van Besien, Koen, Gentile, Teresa, Isola, Luis, Maziarz, Richard T, Gabriel, Don A, Bashey, Asad, Landau, Heather, Martin, Thomas, Qazilbash, Muzaffar H, Levitan, Denise, McClune, Brian, Schlossman, Robert, Hars, Vera, Postiglione, John, Jiang, Chen, Bennett, Elizabeth, Barry, Susan, Bressler, Linda, Kelly, Michael, Seiler, Michele, Rosenbaum, Cara, Hari, Parameswaran, Pasquini, Marcelo C, Horowitz, Mary M, Shea, Thomas C, Devine, Steven M, Anderson, Kenneth C, Linker, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Autografts Cancer Cancer therapies Clinical trials Disease-Free Survival Double-Blind Method Female Follow-Up Studies Humans Immunotherapy Lenalidomide Maintenance Chemotherapy Male Middle Aged Multiple myeloma Multiple Myeloma - drug therapy Multiple Myeloma - mortality Multiple Myeloma - therapy Neoplasms, Second Primary - epidemiology Stem Cell Transplantation Targeted cancer therapy Thalidomide - adverse effects Thalidomide - analogs & derivatives Thalidomide - therapeutic use Toxicity Transplants & implants
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