A Case of Good Syndrome with Pulmonary Lesions Similar to Diffuse Panbronchiolitis
We herein present a case of Good syndrome complicated by diffuse pulmonary lesions similar to diffuse panbronchiolitis (DPB). A 45-year-old Japanese man was referred to our department due to recurrent lower respiratory tract infections that had started and ameliorated nine months after thymectomy fo...
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| Veröffentlicht in: | Internal Medicine 2012, Vol.51(9), pp.1087-1091 |
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| container_issue | 9 |
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| container_title | Internal Medicine |
| container_volume | 51 |
| creator | Ogoshi, Takaaki Ishimoto, Hiroshi Yatera, Kazuhiro Oda, Keishi Akata, Kentarou Yamasaki, Kei Kido, Takashi Kawanami, Toshinori Yoshii, Chiharu Mukae, Hiroshi |
| description | We herein present a case of Good syndrome complicated by diffuse pulmonary lesions similar to diffuse panbronchiolitis (DPB). A 45-year-old Japanese man was referred to our department due to recurrent lower respiratory tract infections that had started and ameliorated nine months after thymectomy for pure red cell aplasia and myasthenia gravis. Diffuse centrilobular opacities on chest computed tomography and positivity for HLA-B54 were consistent with DPB. Additionally, hypogammaglobulinemia and a marked decrease of B-lymphocytes were observed, and therefore Good syndrome was considered. Combination therapy with azithromycin and clarithromycin alleviated the patient's respiratory symptoms and reduced the exacerbation of chronic bronchitis. |
| doi_str_mv | 10.2169/internalmedicine.51.7028 |
| format | Article |
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A 45-year-old Japanese man was referred to our department due to recurrent lower respiratory tract infections that had started and ameliorated nine months after thymectomy for pure red cell aplasia and myasthenia gravis. Diffuse centrilobular opacities on chest computed tomography and positivity for HLA-B54 were consistent with DPB. Additionally, hypogammaglobulinemia and a marked decrease of B-lymphocytes were observed, and therefore Good syndrome was considered. Combination therapy with azithromycin and clarithromycin alleviated the patient's respiratory symptoms and reduced the exacerbation of chronic bronchitis.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.51.7028</identifier><identifier>PMID: 22576393</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Agammaglobulinemia - blood ; Agammaglobulinemia - complications ; Agammaglobulinemia - diagnosis ; azithromycin ; Bronchiolitis - blood ; Bronchiolitis - complications ; Bronchiolitis - diagnosis ; clarithromycin ; diffuse panbronchiolitis ; DPB ; Good syndrome ; Haemophilus Infections - blood ; Haemophilus Infections - complications ; Haemophilus Infections - diagnosis ; HLA-B Antigens - blood ; Humans ; Lung - metabolism ; Lung - pathology ; Male ; Middle Aged ; Syndrome ; Thymoma - blood ; Thymoma - complications ; Thymoma - diagnosis</subject><ispartof>Internal Medicine, 2012, Vol.51(9), pp.1087-1091</ispartof><rights>2012 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-310beeb7b556e793c00dbdf4f6125fb5b8084e4af011268a07ed4a494e3206623</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,1877,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22576393$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ogoshi, Takaaki</creatorcontrib><creatorcontrib>Ishimoto, Hiroshi</creatorcontrib><creatorcontrib>Yatera, Kazuhiro</creatorcontrib><creatorcontrib>Oda, Keishi</creatorcontrib><creatorcontrib>Akata, Kentarou</creatorcontrib><creatorcontrib>Yamasaki, Kei</creatorcontrib><creatorcontrib>Kido, Takashi</creatorcontrib><creatorcontrib>Kawanami, Toshinori</creatorcontrib><creatorcontrib>Yoshii, Chiharu</creatorcontrib><creatorcontrib>Mukae, Hiroshi</creatorcontrib><title>A Case of Good Syndrome with Pulmonary Lesions Similar to Diffuse Panbronchiolitis</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>We herein present a case of Good syndrome complicated by diffuse pulmonary lesions similar to diffuse panbronchiolitis (DPB). A 45-year-old Japanese man was referred to our department due to recurrent lower respiratory tract infections that had started and ameliorated nine months after thymectomy for pure red cell aplasia and myasthenia gravis. Diffuse centrilobular opacities on chest computed tomography and positivity for HLA-B54 were consistent with DPB. Additionally, hypogammaglobulinemia and a marked decrease of B-lymphocytes were observed, and therefore Good syndrome was considered. Combination therapy with azithromycin and clarithromycin alleviated the patient's respiratory symptoms and reduced the exacerbation of chronic bronchitis.</description><subject>Agammaglobulinemia - blood</subject><subject>Agammaglobulinemia - complications</subject><subject>Agammaglobulinemia - diagnosis</subject><subject>azithromycin</subject><subject>Bronchiolitis - blood</subject><subject>Bronchiolitis - complications</subject><subject>Bronchiolitis - diagnosis</subject><subject>clarithromycin</subject><subject>diffuse panbronchiolitis</subject><subject>DPB</subject><subject>Good syndrome</subject><subject>Haemophilus Infections - blood</subject><subject>Haemophilus Infections - complications</subject><subject>Haemophilus Infections - diagnosis</subject><subject>HLA-B Antigens - blood</subject><subject>Humans</subject><subject>Lung - metabolism</subject><subject>Lung - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Syndrome</subject><subject>Thymoma - blood</subject><subject>Thymoma - complications</subject><subject>Thymoma - diagnosis</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkEtPwzAQhC0EgvL4C8hHLil-xLFzrMpTKgJROEdOsqauEhvsRIh_j1FLD4jL7GG_mdUOQpiSKaNFeWndAMHprofWNtbBVNCpJEztoQnleZlJxsU-mpCSqowlOULHMa4J4UqW7BAdMSZkwUs-Qc8zPNcRsDf41vsWL79cG3wP-NMOK_w0dr13OnzhBUTrXcRL29tOBzx4fGWNGZP1Sbs6eNesrO_sYOMpOjC6i3C2nSfo9eb6ZX6XLR5v7-ezRdYIJoaMU1ID1LIWogBZ8oaQtm5NbgrKhKlFrYjKIdeGUMoKpYmENtd5mQNnpCgYP0EXm9z34D9GiEPV29hA12kHfowVJZTJXAnJE6o2aBN8jAFM9R5sn_5KUPXTaPW30UrQ6qfRZD3fXhnrtNwZfytMwMMGWMdBv8EO0GGwTQf_JpcboUTJHdesdKjA8W8NMpQD</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Ogoshi, Takaaki</creator><creator>Ishimoto, Hiroshi</creator><creator>Yatera, Kazuhiro</creator><creator>Oda, Keishi</creator><creator>Akata, Kentarou</creator><creator>Yamasaki, Kei</creator><creator>Kido, Takashi</creator><creator>Kawanami, Toshinori</creator><creator>Yoshii, Chiharu</creator><creator>Mukae, Hiroshi</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120101</creationdate><title>A Case of Good Syndrome with Pulmonary Lesions Similar to Diffuse Panbronchiolitis</title><author>Ogoshi, Takaaki ; Ishimoto, Hiroshi ; Yatera, Kazuhiro ; Oda, Keishi ; Akata, Kentarou ; Yamasaki, Kei ; Kido, Takashi ; Kawanami, Toshinori ; Yoshii, Chiharu ; Mukae, Hiroshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-310beeb7b556e793c00dbdf4f6125fb5b8084e4af011268a07ed4a494e3206623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Agammaglobulinemia - blood</topic><topic>Agammaglobulinemia - complications</topic><topic>Agammaglobulinemia - diagnosis</topic><topic>azithromycin</topic><topic>Bronchiolitis - blood</topic><topic>Bronchiolitis - complications</topic><topic>Bronchiolitis - diagnosis</topic><topic>clarithromycin</topic><topic>diffuse panbronchiolitis</topic><topic>DPB</topic><topic>Good syndrome</topic><topic>Haemophilus Infections - blood</topic><topic>Haemophilus Infections - complications</topic><topic>Haemophilus Infections - diagnosis</topic><topic>HLA-B Antigens - blood</topic><topic>Humans</topic><topic>Lung - metabolism</topic><topic>Lung - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Syndrome</topic><topic>Thymoma - blood</topic><topic>Thymoma - complications</topic><topic>Thymoma - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ogoshi, Takaaki</creatorcontrib><creatorcontrib>Ishimoto, Hiroshi</creatorcontrib><creatorcontrib>Yatera, Kazuhiro</creatorcontrib><creatorcontrib>Oda, Keishi</creatorcontrib><creatorcontrib>Akata, Kentarou</creatorcontrib><creatorcontrib>Yamasaki, Kei</creatorcontrib><creatorcontrib>Kido, Takashi</creatorcontrib><creatorcontrib>Kawanami, Toshinori</creatorcontrib><creatorcontrib>Yoshii, Chiharu</creatorcontrib><creatorcontrib>Mukae, Hiroshi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ogoshi, Takaaki</au><au>Ishimoto, Hiroshi</au><au>Yatera, Kazuhiro</au><au>Oda, Keishi</au><au>Akata, Kentarou</au><au>Yamasaki, Kei</au><au>Kido, Takashi</au><au>Kawanami, Toshinori</au><au>Yoshii, Chiharu</au><au>Mukae, Hiroshi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case of Good Syndrome with Pulmonary Lesions Similar to Diffuse Panbronchiolitis</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>51</volume><issue>9</issue><spage>1087</spage><epage>1091</epage><pages>1087-1091</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>We herein present a case of Good syndrome complicated by diffuse pulmonary lesions similar to diffuse panbronchiolitis (DPB). A 45-year-old Japanese man was referred to our department due to recurrent lower respiratory tract infections that had started and ameliorated nine months after thymectomy for pure red cell aplasia and myasthenia gravis. Diffuse centrilobular opacities on chest computed tomography and positivity for HLA-B54 were consistent with DPB. Additionally, hypogammaglobulinemia and a marked decrease of B-lymphocytes were observed, and therefore Good syndrome was considered. Combination therapy with azithromycin and clarithromycin alleviated the patient's respiratory symptoms and reduced the exacerbation of chronic bronchitis.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>22576393</pmid><doi>10.2169/internalmedicine.51.7028</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | Agammaglobulinemia - blood Agammaglobulinemia - complications Agammaglobulinemia - diagnosis azithromycin Bronchiolitis - blood Bronchiolitis - complications Bronchiolitis - diagnosis clarithromycin diffuse panbronchiolitis DPB Good syndrome Haemophilus Infections - blood Haemophilus Infections - complications Haemophilus Infections - diagnosis HLA-B Antigens - blood Humans Lung - metabolism Lung - pathology Male Middle Aged Syndrome Thymoma - blood Thymoma - complications Thymoma - diagnosis |
| title | A Case of Good Syndrome with Pulmonary Lesions Similar to Diffuse Panbronchiolitis |
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