Apoptosis of Kasumi-1 cells induced by puerariae radix flavones and its molecular mechanism

To explore the effects and the molecular mechanism of puerariae radix flavones (PRF) on acute myeloid leukemia cell line Kasumi-1 cells in vitro. Kasumi-1 cells treated by PRF for 48 hours were observed with Wright's and Hoechst 33258 dying. The apoptotic cells were analyzed by flow cytometry w...

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Veröffentlicht in:	Zhōnghuá xuèyèxué zázhì 2012-01, Vol.33 (1), p.43-46
Hauptverfasser:	Shao, Hua-min, Tang, Yu-hong, Shen, Qun, Zhu, Hong-qing, Ji, Ou, Zhang, Ya-cheng, Ji, Jian-min, Jiang, Peng-jun, Si, Ye-jun, Li, Zhao-rong
Format:	Artikel
Sprache:	chi
Schlagworte:	Apoptosis - drug effects Caspase 3 - metabolism Caspase 8 - metabolism Cell Line, Tumor Core Binding Factor Alpha 2 Subunit - genetics Core Binding Factor Alpha 2 Subunit - metabolism Flavones - pharmacology Humans Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - metabolism Proto-Oncogene Proteins c-bcl-2 - metabolism Pueraria RUNX1 Translocation Partner 1 Protein
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