HBV infection in Belgium: Results of the BASL observatory of 1,456 HBsAg carriers
Nationwide studies are mandatory to assess changes in the epidemiology of HBV infection in Europe. To describe epidemiological characteristics of HBsAg-positive patients, especially inactive carriers, and to evaluate how practitioners manage HBV patients in real life. Belgian physicians were asked t...
Gespeichert in:
| Veröffentlicht in: | Acta gastro-enterologica belgica 2012-03, Vol.75 (1), p.35-41 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 41 |
|---|---|
| container_issue | 1 |
| container_start_page | 35 |
| container_title | Acta gastro-enterologica belgica |
| container_volume | 75 |
| creator | DELTENRE, Pierre LALEMAN, Wim D'HEYGERE, François ROBAEYS, Geert DE GALOCSY, Chantal BRENARD, Réginald LANGLET, Philippe SPRENGERS, Dirk MAIRLOT, Marie-Christine PREUX, Cécile LEFEBVRE, Véronique ORLENT, Hans VAN GOSSUM, Marc HENRION, Jean LENAERTS, Anne COLLE, Isabelle MICHIELSEN, Peter ADLER, Michael DELWAIDE, Jean ASSENE, Collins REYNAERT, Hendrik |
| description | Nationwide studies are mandatory to assess changes in the epidemiology of HBV infection in Europe.
To describe epidemiological characteristics of HBsAg-positive patients, especially inactive carriers, and to evaluate how practitioners manage HBV patients in real life.
Belgian physicians were asked to report all chronically infected HBV patients during a one-year period.
Among 1,456 patients included, 1,035 (71%) were classified into one of four phases of chronic infection: immune tolerance (n = 10), HBeAg-positive hepatitis (n = 248), HBeAg-negative hepatitis (n = 420) and inactive carrier state (n = 357 HBeAg-negative patients with ALT |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1012209103</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1012209103</sourcerecordid><originalsourceid>FETCH-LOGICAL-p171t-395e94efa442158f2c505ede91d94664aad8032fa2a7399053a101af92b5686f3</originalsourceid><addsrcrecordid>eNpF0E1Lw0AQBuA9KLbU_gXZi-DBwH5v1ltTtBUK4uc1TJPZGslH3U2E_nsjVpzLDC8P72FOyJTbVCVSCDsh8xg_2DhOcSbYGZkIoY21Sk_J4zp7o1Xrseirrh0vmmG9q4bmhj5hHOo-0s7T_h1ptnje0G4bMXxB34XDT86vlTZ0ncXFjhYQQoUhnpNTD3XE-XHPyOvd7ctynWweVvfLxSbZc8v7RDqNTqEHpQTXqReFZhpLdLx0yhgFUKZMCg8CrHSOaQmccfBObLVJjZczcvXbuw_d54Cxz5sqFljX0GI3xHzUQjDHmRzpxZEO2wbLfB-qBsIh_3vDCC6PAGIBtQ_QFlX8d2askszKb4fIYkw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1012209103</pqid></control><display><type>article</type><title>HBV infection in Belgium: Results of the BASL observatory of 1,456 HBsAg carriers</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>DELTENRE, Pierre ; LALEMAN, Wim ; D'HEYGERE, François ; ROBAEYS, Geert ; DE GALOCSY, Chantal ; BRENARD, Réginald ; LANGLET, Philippe ; SPRENGERS, Dirk ; MAIRLOT, Marie-Christine ; PREUX, Cécile ; LEFEBVRE, Véronique ; ORLENT, Hans ; VAN GOSSUM, Marc ; HENRION, Jean ; LENAERTS, Anne ; COLLE, Isabelle ; MICHIELSEN, Peter ; ADLER, Michael ; DELWAIDE, Jean ; ASSENE, Collins ; REYNAERT, Hendrik</creator><creatorcontrib>DELTENRE, Pierre ; LALEMAN, Wim ; D'HEYGERE, François ; ROBAEYS, Geert ; DE GALOCSY, Chantal ; BRENARD, Réginald ; LANGLET, Philippe ; SPRENGERS, Dirk ; MAIRLOT, Marie-Christine ; PREUX, Cécile ; LEFEBVRE, Véronique ; ORLENT, Hans ; VAN GOSSUM, Marc ; HENRION, Jean ; LENAERTS, Anne ; COLLE, Isabelle ; MICHIELSEN, Peter ; ADLER, Michael ; DELWAIDE, Jean ; ASSENE, Collins ; REYNAERT, Hendrik</creatorcontrib><description>Nationwide studies are mandatory to assess changes in the epidemiology of HBV infection in Europe.
To describe epidemiological characteristics of HBsAg-positive patients, especially inactive carriers, and to evaluate how practitioners manage HBV patients in real life.
Belgian physicians were asked to report all chronically infected HBV patients during a one-year period.
Among 1,456 patients included, 1,035 (71%) were classified into one of four phases of chronic infection: immune tolerance (n = 10), HBeAg-positive hepatitis (n = 248), HBeAg-negative hepatitis (n = 420) and inactive carrier state (n = 357 HBeAg-negative patients with ALT <upper limit of normal (ULN) and HBV DNA <2,000 IU/mL). Using less restrictive criteria for ALT (1-2 ULN) or HBV DNA (2,000-20,000 IU/mL), 93 unclassified patients were added to the group of inactive carriers. These 93 additional inactive carriers were younger, more frequently males, with similar risk factors for HBV infection and histological features compared to inactive carriers according to recent guidelines. Recent guidelines on management of HBV patients were generally followed, but systematic HBV DNA measurements and HDV co-infection screening should be reinforced.
In Belgium, an inactive carrier state was a common form of chronic HBV infection. Using less restrictive criteria for classification of inactive carriers did not modify their main characteristics and seemed better adapted to clinical practice. Recent guidelines on management of HBV patients should be reinforced.</description><identifier>ISSN: 1784-3227</identifier><identifier>PMID: 22567745</identifier><language>eng</language><publisher>Brussels: Société Royale Belge de Gastro-Entérologie</publisher><subject>Adult ; Belgium - epidemiology ; Biological and medical sciences ; Carrier State ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Hepatitis B Surface Antigens - analysis ; Hepatitis B, Chronic - epidemiology ; Hepatitis B, Chronic - immunology ; Human viral diseases ; Humans ; Immune Tolerance ; Infectious diseases ; Liver. Biliary tract. Portal circulation. Exocrine pancreas ; Male ; Medical sciences ; Other diseases. Semiology ; Viral diseases ; Viral hepatitis</subject><ispartof>Acta gastro-enterologica belgica, 2012-03, Vol.75 (1), p.35-41</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26122307$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22567745$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DELTENRE, Pierre</creatorcontrib><creatorcontrib>LALEMAN, Wim</creatorcontrib><creatorcontrib>D'HEYGERE, François</creatorcontrib><creatorcontrib>ROBAEYS, Geert</creatorcontrib><creatorcontrib>DE GALOCSY, Chantal</creatorcontrib><creatorcontrib>BRENARD, Réginald</creatorcontrib><creatorcontrib>LANGLET, Philippe</creatorcontrib><creatorcontrib>SPRENGERS, Dirk</creatorcontrib><creatorcontrib>MAIRLOT, Marie-Christine</creatorcontrib><creatorcontrib>PREUX, Cécile</creatorcontrib><creatorcontrib>LEFEBVRE, Véronique</creatorcontrib><creatorcontrib>ORLENT, Hans</creatorcontrib><creatorcontrib>VAN GOSSUM, Marc</creatorcontrib><creatorcontrib>HENRION, Jean</creatorcontrib><creatorcontrib>LENAERTS, Anne</creatorcontrib><creatorcontrib>COLLE, Isabelle</creatorcontrib><creatorcontrib>MICHIELSEN, Peter</creatorcontrib><creatorcontrib>ADLER, Michael</creatorcontrib><creatorcontrib>DELWAIDE, Jean</creatorcontrib><creatorcontrib>ASSENE, Collins</creatorcontrib><creatorcontrib>REYNAERT, Hendrik</creatorcontrib><title>HBV infection in Belgium: Results of the BASL observatory of 1,456 HBsAg carriers</title><title>Acta gastro-enterologica belgica</title><addtitle>Acta Gastroenterol Belg</addtitle><description>Nationwide studies are mandatory to assess changes in the epidemiology of HBV infection in Europe.
To describe epidemiological characteristics of HBsAg-positive patients, especially inactive carriers, and to evaluate how practitioners manage HBV patients in real life.
Belgian physicians were asked to report all chronically infected HBV patients during a one-year period.
Among 1,456 patients included, 1,035 (71%) were classified into one of four phases of chronic infection: immune tolerance (n = 10), HBeAg-positive hepatitis (n = 248), HBeAg-negative hepatitis (n = 420) and inactive carrier state (n = 357 HBeAg-negative patients with ALT <upper limit of normal (ULN) and HBV DNA <2,000 IU/mL). Using less restrictive criteria for ALT (1-2 ULN) or HBV DNA (2,000-20,000 IU/mL), 93 unclassified patients were added to the group of inactive carriers. These 93 additional inactive carriers were younger, more frequently males, with similar risk factors for HBV infection and histological features compared to inactive carriers according to recent guidelines. Recent guidelines on management of HBV patients were generally followed, but systematic HBV DNA measurements and HDV co-infection screening should be reinforced.
In Belgium, an inactive carrier state was a common form of chronic HBV infection. Using less restrictive criteria for classification of inactive carriers did not modify their main characteristics and seemed better adapted to clinical practice. Recent guidelines on management of HBV patients should be reinforced.</description><subject>Adult</subject><subject>Belgium - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Carrier State</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Hepatitis B Surface Antigens - analysis</subject><subject>Hepatitis B, Chronic - epidemiology</subject><subject>Hepatitis B, Chronic - immunology</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immune Tolerance</subject><subject>Infectious diseases</subject><subject>Liver. Biliary tract. Portal circulation. Exocrine pancreas</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Viral diseases</subject><subject>Viral hepatitis</subject><issn>1784-3227</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0E1Lw0AQBuA9KLbU_gXZi-DBwH5v1ltTtBUK4uc1TJPZGslH3U2E_nsjVpzLDC8P72FOyJTbVCVSCDsh8xg_2DhOcSbYGZkIoY21Sk_J4zp7o1Xrseirrh0vmmG9q4bmhj5hHOo-0s7T_h1ptnje0G4bMXxB34XDT86vlTZ0ncXFjhYQQoUhnpNTD3XE-XHPyOvd7ctynWweVvfLxSbZc8v7RDqNTqEHpQTXqReFZhpLdLx0yhgFUKZMCg8CrHSOaQmccfBObLVJjZczcvXbuw_d54Cxz5sqFljX0GI3xHzUQjDHmRzpxZEO2wbLfB-qBsIh_3vDCC6PAGIBtQ_QFlX8d2askszKb4fIYkw</recordid><startdate>20120301</startdate><enddate>20120301</enddate><creator>DELTENRE, Pierre</creator><creator>LALEMAN, Wim</creator><creator>D'HEYGERE, François</creator><creator>ROBAEYS, Geert</creator><creator>DE GALOCSY, Chantal</creator><creator>BRENARD, Réginald</creator><creator>LANGLET, Philippe</creator><creator>SPRENGERS, Dirk</creator><creator>MAIRLOT, Marie-Christine</creator><creator>PREUX, Cécile</creator><creator>LEFEBVRE, Véronique</creator><creator>ORLENT, Hans</creator><creator>VAN GOSSUM, Marc</creator><creator>HENRION, Jean</creator><creator>LENAERTS, Anne</creator><creator>COLLE, Isabelle</creator><creator>MICHIELSEN, Peter</creator><creator>ADLER, Michael</creator><creator>DELWAIDE, Jean</creator><creator>ASSENE, Collins</creator><creator>REYNAERT, Hendrik</creator><general>Société Royale Belge de Gastro-Entérologie</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20120301</creationdate><title>HBV infection in Belgium: Results of the BASL observatory of 1,456 HBsAg carriers</title><author>DELTENRE, Pierre ; LALEMAN, Wim ; D'HEYGERE, François ; ROBAEYS, Geert ; DE GALOCSY, Chantal ; BRENARD, Réginald ; LANGLET, Philippe ; SPRENGERS, Dirk ; MAIRLOT, Marie-Christine ; PREUX, Cécile ; LEFEBVRE, Véronique ; ORLENT, Hans ; VAN GOSSUM, Marc ; HENRION, Jean ; LENAERTS, Anne ; COLLE, Isabelle ; MICHIELSEN, Peter ; ADLER, Michael ; DELWAIDE, Jean ; ASSENE, Collins ; REYNAERT, Hendrik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p171t-395e94efa442158f2c505ede91d94664aad8032fa2a7399053a101af92b5686f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Belgium - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Carrier State</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Hepatitis B Surface Antigens - analysis</topic><topic>Hepatitis B, Chronic - epidemiology</topic><topic>Hepatitis B, Chronic - immunology</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immune Tolerance</topic><topic>Infectious diseases</topic><topic>Liver. Biliary tract. Portal circulation. Exocrine pancreas</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Viral diseases</topic><topic>Viral hepatitis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DELTENRE, Pierre</creatorcontrib><creatorcontrib>LALEMAN, Wim</creatorcontrib><creatorcontrib>D'HEYGERE, François</creatorcontrib><creatorcontrib>ROBAEYS, Geert</creatorcontrib><creatorcontrib>DE GALOCSY, Chantal</creatorcontrib><creatorcontrib>BRENARD, Réginald</creatorcontrib><creatorcontrib>LANGLET, Philippe</creatorcontrib><creatorcontrib>SPRENGERS, Dirk</creatorcontrib><creatorcontrib>MAIRLOT, Marie-Christine</creatorcontrib><creatorcontrib>PREUX, Cécile</creatorcontrib><creatorcontrib>LEFEBVRE, Véronique</creatorcontrib><creatorcontrib>ORLENT, Hans</creatorcontrib><creatorcontrib>VAN GOSSUM, Marc</creatorcontrib><creatorcontrib>HENRION, Jean</creatorcontrib><creatorcontrib>LENAERTS, Anne</creatorcontrib><creatorcontrib>COLLE, Isabelle</creatorcontrib><creatorcontrib>MICHIELSEN, Peter</creatorcontrib><creatorcontrib>ADLER, Michael</creatorcontrib><creatorcontrib>DELWAIDE, Jean</creatorcontrib><creatorcontrib>ASSENE, Collins</creatorcontrib><creatorcontrib>REYNAERT, Hendrik</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta gastro-enterologica belgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DELTENRE, Pierre</au><au>LALEMAN, Wim</au><au>D'HEYGERE, François</au><au>ROBAEYS, Geert</au><au>DE GALOCSY, Chantal</au><au>BRENARD, Réginald</au><au>LANGLET, Philippe</au><au>SPRENGERS, Dirk</au><au>MAIRLOT, Marie-Christine</au><au>PREUX, Cécile</au><au>LEFEBVRE, Véronique</au><au>ORLENT, Hans</au><au>VAN GOSSUM, Marc</au><au>HENRION, Jean</au><au>LENAERTS, Anne</au><au>COLLE, Isabelle</au><au>MICHIELSEN, Peter</au><au>ADLER, Michael</au><au>DELWAIDE, Jean</au><au>ASSENE, Collins</au><au>REYNAERT, Hendrik</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>HBV infection in Belgium: Results of the BASL observatory of 1,456 HBsAg carriers</atitle><jtitle>Acta gastro-enterologica belgica</jtitle><addtitle>Acta Gastroenterol Belg</addtitle><date>2012-03-01</date><risdate>2012</risdate><volume>75</volume><issue>1</issue><spage>35</spage><epage>41</epage><pages>35-41</pages><issn>1784-3227</issn><abstract>Nationwide studies are mandatory to assess changes in the epidemiology of HBV infection in Europe.
To describe epidemiological characteristics of HBsAg-positive patients, especially inactive carriers, and to evaluate how practitioners manage HBV patients in real life.
Belgian physicians were asked to report all chronically infected HBV patients during a one-year period.
Among 1,456 patients included, 1,035 (71%) were classified into one of four phases of chronic infection: immune tolerance (n = 10), HBeAg-positive hepatitis (n = 248), HBeAg-negative hepatitis (n = 420) and inactive carrier state (n = 357 HBeAg-negative patients with ALT <upper limit of normal (ULN) and HBV DNA <2,000 IU/mL). Using less restrictive criteria for ALT (1-2 ULN) or HBV DNA (2,000-20,000 IU/mL), 93 unclassified patients were added to the group of inactive carriers. These 93 additional inactive carriers were younger, more frequently males, with similar risk factors for HBV infection and histological features compared to inactive carriers according to recent guidelines. Recent guidelines on management of HBV patients were generally followed, but systematic HBV DNA measurements and HDV co-infection screening should be reinforced.
In Belgium, an inactive carrier state was a common form of chronic HBV infection. Using less restrictive criteria for classification of inactive carriers did not modify their main characteristics and seemed better adapted to clinical practice. Recent guidelines on management of HBV patients should be reinforced.</abstract><cop>Brussels</cop><pub>Société Royale Belge de Gastro-Entérologie</pub><pmid>22567745</pmid><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1784-3227 |
| ispartof | Acta gastro-enterologica belgica, 2012-03, Vol.75 (1), p.35-41 |
| issn | 1784-3227 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1012209103 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Belgium - epidemiology Biological and medical sciences Carrier State Female Gastroenterology. Liver. Pancreas. Abdomen Hepatitis B Surface Antigens - analysis Hepatitis B, Chronic - epidemiology Hepatitis B, Chronic - immunology Human viral diseases Humans Immune Tolerance Infectious diseases Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Other diseases. Semiology Viral diseases Viral hepatitis |
| title | HBV infection in Belgium: Results of the BASL observatory of 1,456 HBsAg carriers |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T10%3A13%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=HBV%20infection%20in%20Belgium:%20Results%20of%20the%20BASL%20observatory%20of%201,456%20HBsAg%20carriers&rft.jtitle=Acta%20gastro-enterologica%20belgica&rft.au=DELTENRE,%20Pierre&rft.date=2012-03-01&rft.volume=75&rft.issue=1&rft.spage=35&rft.epage=41&rft.pages=35-41&rft.issn=1784-3227&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1012209103%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1012209103&rft_id=info:pmid/22567745&rfr_iscdi=true |