Exogenous expression of UHRF1 promotes proliferation and metastasis of breast cancer cells

In the present study, we investigated the role of UHRF1 (ubiquitin-like protein containing PHD and RING finger domains 1) in proliferation, invasion and migration of breast cancer cells, and the potential mechanisms were also explored. Cell proliferation was examined by 3-(4,5-Dimethylthiazol-2-yl)-...

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Veröffentlicht in:	Oncology reports 2012-07, Vol.28 (1), p.375-383
Hauptverfasser:	LI, Xin-Li, XU, Jiu-Hong, NIE, Ji-Hua, FAN, Sai-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - blood supply Adenocarcinoma - metabolism Adenocarcinoma - secondary Animals Apoptosis Apoptosis Regulatory Proteins - metabolism Biological and medical sciences Breast Neoplasms - blood supply Breast Neoplasms - metabolism Breast Neoplasms - pathology CCAAT-Enhancer-Binding Proteins - genetics CCAAT-Enhancer-Binding Proteins - metabolism CCAAT-Enhancer-Binding Proteins - physiology Cell Cycle Checkpoints Cell Line, Tumor Cell Movement Cell Proliferation Cell Survival Female Gene Expression Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Mice Mice, Inbred BALB C Mice, Nude Neoplasm Invasiveness Neoplasm Transplantation Neovascularization, Pathologic - metabolism Tumor Burden Tumors
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