L-carnitine and cancer cachexia. I. L-carnitine distribution and metabolic disorders in cancer cachexia

Cancer cachexia (CC), a progressive loss of body mass, is associated with decreased energy production. Abnormally low levels of L-carnitine (LC) in skeletal muscle means that mitochondrial β-oxidation of long-chain fatty acids (LCFA) does not occur efficiently in patients with CC. We assessed the in...

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Veröffentlicht in:	Oncology reports 2012-07, Vol.28 (1), p.319-323
Hauptverfasser:	SZEFEL, Jaroslaw, JANUSZ KRUSZEWSKI, Wiesław, CIESIELSKI, Maciej, SZAJEWSKI, Mariusz, KAWECKI, Krzysztof, ALEKSANDROWICZ- WRONA, Ewa, JANKUN, Jerzy, YSIAK-SZYDLOWSKA, Wiesławał
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Body Mass Index Cachexia - blood Cachexia - etiology Cachexia - therapy Carnitine - blood Carnitine - metabolism Carnitine - urine Fat Emulsions, Intravenous - administration & dosage Female Humans Male Medical sciences Middle Aged Muscle, Skeletal - metabolism Neoplasms - blood Neoplasms - complications Neoplasms - therapy Reference Values Triglycerides - administration & dosage Tumors
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