Efficacy and Safety of Leuprolide Acetate 3-Month Depot 11.25 Milligrams or 30 Milligrams for the Treatment of Central Precocious Puberty

Context: GnRH agonist (GnRHa) monthly injections are frequently used in the treatment of central precocious puberty (CPP). The 3-month leuprolide depot 11.25- and 30-mg formulations are newly approved treatment options. Objective: The aim of the study was to investigate the safety and efficacy of le...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2012-05, Vol.97 (5), p.1572-1580
Hauptverfasser:	Lee, Peter A, Klein, Karen, Mauras, Nelly, Neely, E. Kirk, Bloch, Clifford A, Larsen, Lois, Mattia-Goldberg, Cynthia, Chwalisz, Kristof
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Child Child, Preschool Dose-Response Relationship, Drug Endocrinopathies Estradiol - blood Feeding. Feeding behavior Female Follicle Stimulating Hormone - blood Fundamental and applied biological sciences. Psychology Humans Infant Leuprolide - administration & dosage Leuprolide - adverse effects Leuprolide - therapeutic use Luteinizing Hormone - blood Male Medical sciences Puberty, Precocious - blood Puberty, Precocious - drug therapy Testosterone - blood Treatment Outcome Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology
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