THE SYNERGISTIC EFFECTS OF STARLING FLOWS AND A DISTRIBUTED AND DELOCALIZED NUTRIENT SOURCE ON BONE MARROW STROMAL CELL CULTURE IN HOLLOW FIBRE MEMBRANE BIOREACTORS

Objectives: The development of large dimensions bone tissue engineered constructs is limited by the difficult delivery of nutrients to cells situated in the inner part of them. In this study, hollow fibre membrane bioreactors (HFMB) were used to allow a distributed and delocalized nutrients supply i...

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Veröffentlicht in:International journal of artificial organs 2011-08, Vol.34 (8), p.689-690
Hauptverfasser: De Napoli, IE, Scaglione, S, Giannoni, P, Quarto, R, Catapano, G
Format: Artikel
Sprache:eng
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