The involvement of the HO-1 pathway in the anti-inflammatory action of a sulfated polysaccharide isolated from the red seaweed Gracilaria birdiae

Objectives The aim of this study was to investigate the involvement of the hemoxigenase-1 (HO-1) pathway in the anti-inflammatory action of a sulfated polysaccharide from the red seaweed Gracilaria birdiae (SP-Gb) . Methods SP-Gb (5, 10 and 20 mg/kg) was administered to Wistar rats in a peritonitis...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Inflammation research 2011-12, Vol.60 (12), p.1121-1130
Hauptverfasser:	de Sousa Oliveira Vanderlei, Edfranck, de Araújo, Ianna Wivianne Fernandes, Quinderé, Ana Luíza Gomes, Fontes, Bruno Pedrosa, Eloy, Ygor Raphael Gomes, Rodrigues, José Ariévilo Gurgel, Silva, Antonio Alfredo Rodrigues e, Chaves, Hellíada Vasconcelos, Jorge, Roberta Jeane Bezerra, de Menezes, Dalgimar Beserra, Evangelista, Janaína Serra Azul Monteiro, Bezerra, Mirna Marques, Benevides, Norma Maria Barros
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergology Animals Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Biomedical and Life Sciences Biomedicine Carrageenan Dermatology Dextrans Edema - chemically induced Edema - drug therapy Edema - immunology Enzyme Inhibitors - pharmacology Gracilaria - chemistry Gracilaria birdiae Heme Oxygenase-1 - antagonists & inhibitors Heme Oxygenase-1 - immunology Immunology Leukocyte Count Male Mice Neurology Original Research Paper Peritonitis - chemically induced Peritonitis - drug therapy Peritonitis - immunology Peroxidase - metabolism Pharmacology/Toxicology Polysaccharides - isolation & purification Polysaccharides - pharmacology Polysaccharides - therapeutic use Protoporphyrins - pharmacology Rats Rats, Wistar Rheumatology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!