Radiation-induced cardiac damage in early left breast cancer patients: Risk factors, biological mechanisms, radiobiology, and dosimetric constraints

Abstract Today there is general awareness of the potential damage to the heart in left-sided (more than in right-sided) breast cancer radiotherapy (RT). Historical changes in tumor and heart doses are presented here along with the impact of different RT techniques and volumes. Individual and pharmac...

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Veröffentlicht in:	Radiotherapy and oncology 2012-05, Vol.103 (2), p.133-142
Hauptverfasser:	Sardaro, Angela, Petruzzelli, Maria Fonte, D’Errico, Maria Patrizia, Grimaldi, Luca, Pili, Giorgio, Portaluri, Maurizio
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological parameters Breast cancer Breast Neoplasms - radiotherapy Cardiac damage Dosimetric constraints Female Heart - radiation effects Hematology, Oncology and Palliative Medicine Humans Radiation Tolerance Radiotherapy Radiotherapy Dosage Risk Factors Tomography, Emission-Computed, Single-Photon
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