Construction of functional aliphatic polycarbonates for biomedical applications
Aliphatic polycarbonates are one important kind of biodegradable polymers and have been commonly used as integral components of engineered tissues, medical devices and drug delivery systems. As far as the biomedical application is concerned, traditional aliphatic polycarbonates usually suffer from t...
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| Veröffentlicht in: | Progress in polymer science 2012-02, Vol.37 (2), p.211-236 |
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| container_title | Progress in polymer science |
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| creator | Feng, Jun Zhuo, Ren-Xi Zhang, Xian-Zheng |
| description | Aliphatic polycarbonates are one important kind of biodegradable polymers and have been commonly used as integral components of engineered tissues, medical devices and drug delivery systems. As far as the biomedical application is concerned, traditional aliphatic polycarbonates usually suffer from the strong hydrophobicity, deficient functionality, and insufficient compatibility with cell/organs. Consequently, the application is quite limited in scope. Due to the imparted appealing properties, aliphatic polycarbonates bearing specifically designed functional/reactive groups attract great interest from researchers in the recent years. The present review outlines the development up to date concerning the design and biomedical application of functional aliphatic polycarbonates, with an emphasis on their ring-opening (co)polymerization preparation. |
| doi_str_mv | 10.1016/j.progpolymsci.2011.07.008 |
| format | Article |
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As far as the biomedical application is concerned, traditional aliphatic polycarbonates usually suffer from the strong hydrophobicity, deficient functionality, and insufficient compatibility with cell/organs. Consequently, the application is quite limited in scope. Due to the imparted appealing properties, aliphatic polycarbonates bearing specifically designed functional/reactive groups attract great interest from researchers in the recent years. The present review outlines the development up to date concerning the design and biomedical application of functional aliphatic polycarbonates, with an emphasis on their ring-opening (co)polymerization preparation.</description><subject>Aliphatic compounds</subject><subject>Biocompatibility</subject><subject>Biodegradability</subject><subject>Biomedical application</subject><subject>Cyclic carbonate</subject><subject>Design engineering</subject><subject>Functional aliphatic polycarbonate</subject><subject>Hydrophobicity</subject><subject>Organs</subject><subject>Polycarbonates</subject><subject>Ring-opening polymerization</subject><subject>Surgical implants</subject><issn>0079-6700</issn><issn>1873-1619</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNkM1OwzAQhC0EEqXwDhEnLgm7TWO73FD5lSr1AmfLddbgKomDnSDx9jiUA0dOu1p9M6sZxi4RCgTk1_uiD_6t981XG40rFoBYgCgA5BGboRRljhxXx2wGIFY5FwCn7CzGPQAKrMSMbde-i0MYzeB8l3mb2bH72XWT6cb173pwJpseGB126TxQzKwP2c75lmpnJq7vm7RMqnjOTqxuIl38zjl7fbh_WT_lm-3j8_p2k5vlohxyDZVAWYGBmngNdYUIogTBLS6lrMSOg4R0JAECF5XmaCWS1WYppLEkyzm7Ovim_B8jxUG1LhpqGt2RH6NK7UAyWq3KhN4cUBN8jIGs6oNrdfhK0MRxtVd_W1RTiwqESi0m8d1BTCnMp6OgEkGdSdEDmUHV3v3H5htujYN2</recordid><startdate>20120201</startdate><enddate>20120201</enddate><creator>Feng, Jun</creator><creator>Zhuo, Ren-Xi</creator><creator>Zhang, Xian-Zheng</creator><general>Elsevier Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>20120201</creationdate><title>Construction of functional aliphatic polycarbonates for biomedical applications</title><author>Feng, Jun ; Zhuo, Ren-Xi ; Zhang, Xian-Zheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-a0571850c0de6d0d511073076f148857b6080511e707125a61f81efac478cfe83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aliphatic compounds</topic><topic>Biocompatibility</topic><topic>Biodegradability</topic><topic>Biomedical application</topic><topic>Cyclic carbonate</topic><topic>Design engineering</topic><topic>Functional aliphatic polycarbonate</topic><topic>Hydrophobicity</topic><topic>Organs</topic><topic>Polycarbonates</topic><topic>Ring-opening polymerization</topic><topic>Surgical implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Feng, Jun</creatorcontrib><creatorcontrib>Zhuo, Ren-Xi</creatorcontrib><creatorcontrib>Zhang, Xian-Zheng</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Progress in polymer science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Feng, Jun</au><au>Zhuo, Ren-Xi</au><au>Zhang, Xian-Zheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Construction of functional aliphatic polycarbonates for biomedical applications</atitle><jtitle>Progress in polymer science</jtitle><date>2012-02-01</date><risdate>2012</risdate><volume>37</volume><issue>2</issue><spage>211</spage><epage>236</epage><pages>211-236</pages><issn>0079-6700</issn><eissn>1873-1619</eissn><abstract>Aliphatic polycarbonates are one important kind of biodegradable polymers and have been commonly used as integral components of engineered tissues, medical devices and drug delivery systems. 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| ispartof | Progress in polymer science, 2012-02, Vol.37 (2), p.211-236 |
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| language | eng |
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| source | Access via ScienceDirect (Elsevier) |
| subjects | Aliphatic compounds Biocompatibility Biodegradability Biomedical application Cyclic carbonate Design engineering Functional aliphatic polycarbonate Hydrophobicity Organs Polycarbonates Ring-opening polymerization Surgical implants |
| title | Construction of functional aliphatic polycarbonates for biomedical applications |
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