Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD
Cardiovascular disease is common in chronic obstructive pulmonary disease (COPD) and raised troponin is common in exacerbations. However, the prevalence of myocardial infarction following hospitalisation for exacerbation of COPD is unknown. Patients aged ≥ 40 yrs hospitalised with acute exacerbation...
Gespeichert in:
| Veröffentlicht in: | The European respiratory journal 2012-05, Vol.39 (5), p.1097-1103 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1103 |
|---|---|
| container_issue | 5 |
| container_start_page | 1097 |
| container_title | The European respiratory journal |
| container_volume | 39 |
| creator | MCALLISTER, David A MACLAY, John D CLARK, Elaine MACFARLANE, Peter W MACNEE, William MILLS, Nicholas L LEITCH, Andrew REID, Philip CARRUTHERS, Ross O'CONNOR, Jennifer MCALPINE, Lawrence CHALMERS, George NEWBY, David E |
| description | Cardiovascular disease is common in chronic obstructive pulmonary disease (COPD) and raised troponin is common in exacerbations. However, the prevalence of myocardial infarction following hospitalisation for exacerbation of COPD is unknown. Patients aged ≥ 40 yrs hospitalised with acute exacerbation of COPD (n = 242) with ≥ 10 pack-yrs of cigarette smoking were included in a prospective case series conducted in four hospitals. Patients whose primary presenting complaint was chest pain or who had an alternative diagnosis were excluded. Chest pain histories, serial ECGs and troponin levels were obtained. The mean ± SD age was 69 ± 9 yrs; 108 (45%) patients were male and almost half were current smokers. 124 (51%; 95% CI 48-58%) patients had chest pain, which was exertional in 62 (26%). 24 (10%) had raised troponin, among whom, 20 (8.3%; 95% CI 5.1-12.5%) had chest pain and/or serial ECG changes, fulfilling the 2007 Universal Definition of Myocardial Infarction. Neither chest pain (p = 0.77) nor serial ECG changes (p = 0.39) were associated with raised troponin. Raised troponin, chest pain and serial ECG changes are common in patients admitted to hospital with exacerbation of COPD. Overall, one in 12 patients met the criteria for myocardial infarction. Whether these patients would benefit from further cardiac investigation is unknown. |
| doi_str_mv | 10.1183/09031936.00124811 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1010635480</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1010635480</sourcerecordid><originalsourceid>FETCH-LOGICAL-c374t-441c9cfc353765193ec2e923e0c9eef1c1bb36a9ac9934eaef26b6ca351fc54a3</originalsourceid><addsrcrecordid>eNpFkE1PwkAQhjdGI4j-AC-mFxMvxZ3OtnSPBj8TEjzIuZkOu7imdHEXov57SwA9TTLzvG8mjxCXIIcAJd5KLRE0FkMpIVMlwJHoA2qdopR4LPrbe7oFeuIsxo-OKhTCqehlGWaYj1RfzO4dLVofXUy8TZY_ninMHTWJay0FXjvfJtY3jf9y7SJ593Hl1tS4SPtLSMw3sQn1btF1jKev9-fixFITzcV-DsTs8eFt_JxOpk8v47tJyjhS61QpYM2WMcdRkXePGs6MztBI1sZYYKhrLEgTa43KkLFZURdMmIPlXBEOxM2udxX858bEdbV0kU3TUGv8JlYgQRaYq1J2KOxQDj7GYGy1Cm5J4aeDqq3N6mCzOtjsMlf7-k29NPO_xEFfB1zvAYpMjQ3Usov_XF7mElSJv9olfRI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1010635480</pqid></control><display><type>article</type><title>Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>MCALLISTER, David A ; MACLAY, John D ; CLARK, Elaine ; MACFARLANE, Peter W ; MACNEE, William ; MILLS, Nicholas L ; LEITCH, Andrew ; REID, Philip ; CARRUTHERS, Ross ; O'CONNOR, Jennifer ; MCALPINE, Lawrence ; CHALMERS, George ; NEWBY, David E</creator><creatorcontrib>MCALLISTER, David A ; MACLAY, John D ; CLARK, Elaine ; MACFARLANE, Peter W ; MACNEE, William ; MILLS, Nicholas L ; LEITCH, Andrew ; REID, Philip ; CARRUTHERS, Ross ; O'CONNOR, Jennifer ; MCALPINE, Lawrence ; CHALMERS, George ; NEWBY, David E</creatorcontrib><description>Cardiovascular disease is common in chronic obstructive pulmonary disease (COPD) and raised troponin is common in exacerbations. However, the prevalence of myocardial infarction following hospitalisation for exacerbation of COPD is unknown. Patients aged ≥ 40 yrs hospitalised with acute exacerbation of COPD (n = 242) with ≥ 10 pack-yrs of cigarette smoking were included in a prospective case series conducted in four hospitals. Patients whose primary presenting complaint was chest pain or who had an alternative diagnosis were excluded. Chest pain histories, serial ECGs and troponin levels were obtained. The mean ± SD age was 69 ± 9 yrs; 108 (45%) patients were male and almost half were current smokers. 124 (51%; 95% CI 48-58%) patients had chest pain, which was exertional in 62 (26%). 24 (10%) had raised troponin, among whom, 20 (8.3%; 95% CI 5.1-12.5%) had chest pain and/or serial ECG changes, fulfilling the 2007 Universal Definition of Myocardial Infarction. Neither chest pain (p = 0.77) nor serial ECG changes (p = 0.39) were associated with raised troponin. Raised troponin, chest pain and serial ECG changes are common in patients admitted to hospital with exacerbation of COPD. Overall, one in 12 patients met the criteria for myocardial infarction. Whether these patients would benefit from further cardiac investigation is unknown.</description><identifier>ISSN: 0903-1936</identifier><identifier>EISSN: 1399-3003</identifier><identifier>DOI: 10.1183/09031936.00124811</identifier><identifier>PMID: 22323574</identifier><language>eng</language><publisher>Leeds: Maney</publisher><subject>Aged ; Aged, 80 and over ; Biological and medical sciences ; Cardiology. Vascular system ; Chest Pain - blood ; Chest Pain - diagnosis ; Chest Pain - epidemiology ; Chronic obstructive pulmonary disease, asthma ; Coronary heart disease ; Disease Progression ; Electrocardiography ; Female ; Heart ; Hospitalization - statistics & numerical data ; Humans ; Male ; Medical sciences ; Middle Aged ; Myocardial Infarction - blood ; Myocardial Infarction - diagnosis ; Myocardial Infarction - epidemiology ; Myocarditis. Cardiomyopathies ; Pneumology ; Prevalence ; Prospective Studies ; Pulmonary Disease, Chronic Obstructive - blood ; Pulmonary Disease, Chronic Obstructive - complications ; Smoking - blood ; Smoking - epidemiology ; Troponin - blood</subject><ispartof>The European respiratory journal, 2012-05, Vol.39 (5), p.1097-1103</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-441c9cfc353765193ec2e923e0c9eef1c1bb36a9ac9934eaef26b6ca351fc54a3</citedby><cites>FETCH-LOGICAL-c374t-441c9cfc353765193ec2e923e0c9eef1c1bb36a9ac9934eaef26b6ca351fc54a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25850148$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22323574$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MCALLISTER, David A</creatorcontrib><creatorcontrib>MACLAY, John D</creatorcontrib><creatorcontrib>CLARK, Elaine</creatorcontrib><creatorcontrib>MACFARLANE, Peter W</creatorcontrib><creatorcontrib>MACNEE, William</creatorcontrib><creatorcontrib>MILLS, Nicholas L</creatorcontrib><creatorcontrib>LEITCH, Andrew</creatorcontrib><creatorcontrib>REID, Philip</creatorcontrib><creatorcontrib>CARRUTHERS, Ross</creatorcontrib><creatorcontrib>O'CONNOR, Jennifer</creatorcontrib><creatorcontrib>MCALPINE, Lawrence</creatorcontrib><creatorcontrib>CHALMERS, George</creatorcontrib><creatorcontrib>NEWBY, David E</creatorcontrib><title>Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD</title><title>The European respiratory journal</title><addtitle>Eur Respir J</addtitle><description>Cardiovascular disease is common in chronic obstructive pulmonary disease (COPD) and raised troponin is common in exacerbations. However, the prevalence of myocardial infarction following hospitalisation for exacerbation of COPD is unknown. Patients aged ≥ 40 yrs hospitalised with acute exacerbation of COPD (n = 242) with ≥ 10 pack-yrs of cigarette smoking were included in a prospective case series conducted in four hospitals. Patients whose primary presenting complaint was chest pain or who had an alternative diagnosis were excluded. Chest pain histories, serial ECGs and troponin levels were obtained. The mean ± SD age was 69 ± 9 yrs; 108 (45%) patients were male and almost half were current smokers. 124 (51%; 95% CI 48-58%) patients had chest pain, which was exertional in 62 (26%). 24 (10%) had raised troponin, among whom, 20 (8.3%; 95% CI 5.1-12.5%) had chest pain and/or serial ECG changes, fulfilling the 2007 Universal Definition of Myocardial Infarction. Neither chest pain (p = 0.77) nor serial ECG changes (p = 0.39) were associated with raised troponin. Raised troponin, chest pain and serial ECG changes are common in patients admitted to hospital with exacerbation of COPD. Overall, one in 12 patients met the criteria for myocardial infarction. Whether these patients would benefit from further cardiac investigation is unknown.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Chest Pain - blood</subject><subject>Chest Pain - diagnosis</subject><subject>Chest Pain - epidemiology</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Coronary heart disease</subject><subject>Disease Progression</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Heart</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - blood</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Myocarditis. Cardiomyopathies</subject><subject>Pneumology</subject><subject>Prevalence</subject><subject>Prospective Studies</subject><subject>Pulmonary Disease, Chronic Obstructive - blood</subject><subject>Pulmonary Disease, Chronic Obstructive - complications</subject><subject>Smoking - blood</subject><subject>Smoking - epidemiology</subject><subject>Troponin - blood</subject><issn>0903-1936</issn><issn>1399-3003</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1PwkAQhjdGI4j-AC-mFxMvxZ3OtnSPBj8TEjzIuZkOu7imdHEXov57SwA9TTLzvG8mjxCXIIcAJd5KLRE0FkMpIVMlwJHoA2qdopR4LPrbe7oFeuIsxo-OKhTCqehlGWaYj1RfzO4dLVofXUy8TZY_ninMHTWJay0FXjvfJtY3jf9y7SJ593Hl1tS4SPtLSMw3sQn1btF1jKev9-fixFITzcV-DsTs8eFt_JxOpk8v47tJyjhS61QpYM2WMcdRkXePGs6MztBI1sZYYKhrLEgTa43KkLFZURdMmIPlXBEOxM2udxX858bEdbV0kU3TUGv8JlYgQRaYq1J2KOxQDj7GYGy1Cm5J4aeDqq3N6mCzOtjsMlf7-k29NPO_xEFfB1zvAYpMjQ3Usov_XF7mElSJv9olfRI</recordid><startdate>20120501</startdate><enddate>20120501</enddate><creator>MCALLISTER, David A</creator><creator>MACLAY, John D</creator><creator>CLARK, Elaine</creator><creator>MACFARLANE, Peter W</creator><creator>MACNEE, William</creator><creator>MILLS, Nicholas L</creator><creator>LEITCH, Andrew</creator><creator>REID, Philip</creator><creator>CARRUTHERS, Ross</creator><creator>O'CONNOR, Jennifer</creator><creator>MCALPINE, Lawrence</creator><creator>CHALMERS, George</creator><creator>NEWBY, David E</creator><general>Maney</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120501</creationdate><title>Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD</title><author>MCALLISTER, David A ; MACLAY, John D ; CLARK, Elaine ; MACFARLANE, Peter W ; MACNEE, William ; MILLS, Nicholas L ; LEITCH, Andrew ; REID, Philip ; CARRUTHERS, Ross ; O'CONNOR, Jennifer ; MCALPINE, Lawrence ; CHALMERS, George ; NEWBY, David E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-441c9cfc353765193ec2e923e0c9eef1c1bb36a9ac9934eaef26b6ca351fc54a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>Chest Pain - blood</topic><topic>Chest Pain - diagnosis</topic><topic>Chest Pain - epidemiology</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Coronary heart disease</topic><topic>Disease Progression</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Heart</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - blood</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Myocarditis. Cardiomyopathies</topic><topic>Pneumology</topic><topic>Prevalence</topic><topic>Prospective Studies</topic><topic>Pulmonary Disease, Chronic Obstructive - blood</topic><topic>Pulmonary Disease, Chronic Obstructive - complications</topic><topic>Smoking - blood</topic><topic>Smoking - epidemiology</topic><topic>Troponin - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MCALLISTER, David A</creatorcontrib><creatorcontrib>MACLAY, John D</creatorcontrib><creatorcontrib>CLARK, Elaine</creatorcontrib><creatorcontrib>MACFARLANE, Peter W</creatorcontrib><creatorcontrib>MACNEE, William</creatorcontrib><creatorcontrib>MILLS, Nicholas L</creatorcontrib><creatorcontrib>LEITCH, Andrew</creatorcontrib><creatorcontrib>REID, Philip</creatorcontrib><creatorcontrib>CARRUTHERS, Ross</creatorcontrib><creatorcontrib>O'CONNOR, Jennifer</creatorcontrib><creatorcontrib>MCALPINE, Lawrence</creatorcontrib><creatorcontrib>CHALMERS, George</creatorcontrib><creatorcontrib>NEWBY, David E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The European respiratory journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MCALLISTER, David A</au><au>MACLAY, John D</au><au>CLARK, Elaine</au><au>MACFARLANE, Peter W</au><au>MACNEE, William</au><au>MILLS, Nicholas L</au><au>LEITCH, Andrew</au><au>REID, Philip</au><au>CARRUTHERS, Ross</au><au>O'CONNOR, Jennifer</au><au>MCALPINE, Lawrence</au><au>CHALMERS, George</au><au>NEWBY, David E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD</atitle><jtitle>The European respiratory journal</jtitle><addtitle>Eur Respir J</addtitle><date>2012-05-01</date><risdate>2012</risdate><volume>39</volume><issue>5</issue><spage>1097</spage><epage>1103</epage><pages>1097-1103</pages><issn>0903-1936</issn><eissn>1399-3003</eissn><abstract>Cardiovascular disease is common in chronic obstructive pulmonary disease (COPD) and raised troponin is common in exacerbations. However, the prevalence of myocardial infarction following hospitalisation for exacerbation of COPD is unknown. Patients aged ≥ 40 yrs hospitalised with acute exacerbation of COPD (n = 242) with ≥ 10 pack-yrs of cigarette smoking were included in a prospective case series conducted in four hospitals. Patients whose primary presenting complaint was chest pain or who had an alternative diagnosis were excluded. Chest pain histories, serial ECGs and troponin levels were obtained. The mean ± SD age was 69 ± 9 yrs; 108 (45%) patients were male and almost half were current smokers. 124 (51%; 95% CI 48-58%) patients had chest pain, which was exertional in 62 (26%). 24 (10%) had raised troponin, among whom, 20 (8.3%; 95% CI 5.1-12.5%) had chest pain and/or serial ECG changes, fulfilling the 2007 Universal Definition of Myocardial Infarction. Neither chest pain (p = 0.77) nor serial ECG changes (p = 0.39) were associated with raised troponin. Raised troponin, chest pain and serial ECG changes are common in patients admitted to hospital with exacerbation of COPD. Overall, one in 12 patients met the criteria for myocardial infarction. Whether these patients would benefit from further cardiac investigation is unknown.</abstract><cop>Leeds</cop><pub>Maney</pub><pmid>22323574</pmid><doi>10.1183/09031936.00124811</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0903-1936 |
| ispartof | The European respiratory journal, 2012-05, Vol.39 (5), p.1097-1103 |
| issn | 0903-1936 1399-3003 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1010635480 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Aged Aged, 80 and over Biological and medical sciences Cardiology. Vascular system Chest Pain - blood Chest Pain - diagnosis Chest Pain - epidemiology Chronic obstructive pulmonary disease, asthma Coronary heart disease Disease Progression Electrocardiography Female Heart Hospitalization - statistics & numerical data Humans Male Medical sciences Middle Aged Myocardial Infarction - blood Myocardial Infarction - diagnosis Myocardial Infarction - epidemiology Myocarditis. Cardiomyopathies Pneumology Prevalence Prospective Studies Pulmonary Disease, Chronic Obstructive - blood Pulmonary Disease, Chronic Obstructive - complications Smoking - blood Smoking - epidemiology Troponin - blood |
| title | Diagnosis of myocardial infarction following hospitalisation for exacerbation of COPD |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T03%3A42%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Diagnosis%20of%20myocardial%20infarction%20following%20hospitalisation%20for%20exacerbation%20of%20COPD&rft.jtitle=The%20European%20respiratory%20journal&rft.au=MCALLISTER,%20David%20A&rft.date=2012-05-01&rft.volume=39&rft.issue=5&rft.spage=1097&rft.epage=1103&rft.pages=1097-1103&rft.issn=0903-1936&rft.eissn=1399-3003&rft_id=info:doi/10.1183/09031936.00124811&rft_dat=%3Cproquest_cross%3E1010635480%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1010635480&rft_id=info:pmid/22323574&rfr_iscdi=true |