Successful Treatment of T4 Renal Cell Carcinoma After a Neoadjuvant Targeted Therapy Using Sunitinib: Report of a Case
Since the introduction of targeted therapy, treatment of metastatic renal cell carcinoma (RCC) has undergone dramatic changes. Responses to targeted therapy within the primary tumor and metastatic lesions are novel findings not seen with immunotherapeutic-based strategies. We report here a case of T...
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| Veröffentlicht in: | Kurume medical journal 2011/11/30, Vol.58(3), pp.95-98 |
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| container_title | Kurume medical journal |
| container_volume | 58 |
| creator | UEDA, KOUSUKE NOGUCHI, MASANORI SUEKANE, SIGETAKA MORIYA, FUKUKO NAGAYOSHI, RIKAKO EJIMA, KAZUHISA MOMOZONO, KOUSUKE MATSUOKA, KEI |
| description | Since the introduction of targeted therapy, treatment of metastatic renal cell carcinoma (RCC) has undergone dramatic changes. Responses to targeted therapy within the primary tumor and metastatic lesions are novel findings not seen with immunotherapeutic-based strategies. We report here a case of T4 RCC in which cytoreductive nephrectomy became possible after a neoadjuvant targeted therapy using sunitinib. Our experience with the present case suggests that targeted therapy in the neoadjuvant setting may have a variety of potential applications. Further investigations should be encouraged. |
| doi_str_mv | 10.2739/kurumemedj.58.95 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0023-5679 |
| ispartof | The Kurume Medical Journal, 2011/11/30, Vol.58(3), pp.95-98 |
| issn | 0023-5679 1881-2090 |
| language | eng |
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| source | MEDLINE; EZB Free E-Journals; J-STAGE |
| subjects | Aged Antineoplastic Agents - therapeutic use Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - surgery Humans Indoles - therapeutic use Kidney Neoplasms - drug therapy Kidney Neoplasms - surgery Male Neoadjuvant Therapy Nephrectomy Pyrroles - therapeutic use renal cell carcinoma, sunitinib Treatment Outcome tyrosine kinase inhibitors |
| title | Successful Treatment of T4 Renal Cell Carcinoma After a Neoadjuvant Targeted Therapy Using Sunitinib: Report of a Case |
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