The neurofibromin 1 type I isoform predominance characterises female population affected by sporadic breast cancer: preliminary data

AimsNeurofibromin 1 (NF1) as a tumour suppressor gene can give rise to several transcripts by an alternative splicing event, generated at least for CELF cofactors. At present, the NF1 isoforms and CELF splicing transcripts in sporadic breast cancer are unknown. The aim of the authors was to detect N...

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Veröffentlicht in:	Journal of clinical pathology 2012-05, Vol.65 (5), p.419-423
Hauptverfasser:	Marrero, Daniel, Peralta, Raúl, Valdivia, Alejandra, De la Mora, Antonio, Romero, Pablo, Parra, Miriam, Mendoza, Nayeli, Mendoza, Monica, Rodriguez, Dalila, Camacho, Ernesto, Duarte, Armando, Castelazo, German, Vanegas, Enrique, Garcia, Israel, Vargas, Claudia, Arenas, Diego, Jimenez, Florinda, Salcedo, Mauricio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Biological and medical sciences breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - pathology Carcinoma, Intraductal, Noninfiltrating - genetics Carcinoma, Intraductal, Noninfiltrating - metabolism Carcinoma, Intraductal, Noninfiltrating - pathology CCAAT-Enhancer-Binding Protein-delta - genetics CCAAT-Enhancer-Binding Protein-delta - metabolism CELFs Disease Progression expression Female Fibroadenoma - genetics Fibroadenoma - metabolism Fibroadenoma - pathology Fibrocystic Breast Disease - genetics Fibrocystic Breast Disease - metabolism Fibrocystic Breast Disease - pathology Gene Expression Gene Expression Profiling Genetic Predisposition to Disease Gynecology. Andrology. Obstetrics Humans Investigative techniques, diagnostic techniques (general aspects) isoforms Mammary gland diseases Medical sciences Middle Aged Neurofibromin 1 - genetics Neurofibromin 1 - metabolism NF1 Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Protein Isoforms Tissue Array Analysis Tumors Young Adult
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