F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor and its prognosis is significantly poorer than those of less malignant gliomas. Pathologically, necrosis is one of the most important characteristics that differentiate GBM from lower grade gliomas; therefore, we hypothesized t...

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Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2012-05, Vol.39 (5), p.760-770
Hauptverfasser:	Hirata, Kenji, Terasaka, Shunsuke, Shiga, Tohru, Hattori, Naoya, Magota, Keiichi, Kobayashi, Hiroyuki, Yamaguchi, Shigeru, Houkin, Kiyohiro, Tanaka, Shinya, Kuge, Yuji, Tamaki, Nagara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anaplasia Biological Transport Brain Neoplasms - diagnostic imaging Brain Neoplasms - metabolism Brain Neoplasms - pathology Diagnosis, Differential Female Glioblastoma - diagnostic imaging Glioblastoma - metabolism Glioblastoma - pathology Glioma - diagnostic imaging Glioma - metabolism Glioma - pathology Humans Male Middle Aged Misonidazole - analogs & derivatives Misonidazole - metabolism Neoplasm Grading Positron-Emission Tomography
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