Once daily insulin detemir in cystic fibrosis with insulin deficiency

The aim of this study was to determine if once daily insulin detemir reverses decline in weight and lung function in patients with cystic fibrosis (CF). 12 patients with early insulin deficiency and six with CF related diabetes (aged 7.2–18.1 years) were treated for a median of 0.8 years. Changes in...

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Veröffentlicht in:	Archives of disease in childhood 2012-05, Vol.97 (5), p.464-467
Hauptverfasser:	Hameed, Shihab, Morton, John R, Field, Penny I, Belessis, Yvonne, Yoong, Terence, Katz, Tamarah, Woodhead, Helen J, Walker, Jan L, Neville, Kristen A, Campbell, Thomas A, Jaffé, Adam, Verge, Charles F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences Blood Glucose - metabolism Blood Glucose Self-Monitoring - methods Body Composition Child Cystic fibrosis Cystic Fibrosis - complications Cystic Fibrosis - physiopathology Diabetes Diabetes Mellitus - drug therapy Diabetes Mellitus - etiology Diabetes Mellitus - physiopathology Diabetes therapy Dosage and administration Dose-response relationship Dose-response relationship (Biochemistry) Drug Administration Schedule Drug therapy Errors of metabolism Female Forced Expiratory Volume - drug effects General aspects Glucose Humans Hyperglycemia Hypoglycemia Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - pharmacology Hypoglycemic Agents - therapeutic use Insulin Insulin - deficiency Insulin Detemir Insulin, Long-Acting - administration & dosage Insulin, Long-Acting - pharmacology Insulin, Long-Acting - therapeutic use Male Medical sciences Metabolic diseases Miscellaneous Miscellaneous hereditary metabolic disorders Patient outcomes Patients Population decline Prediabetic State - drug therapy Prediabetic State - etiology Prediabetic State - physiopathology Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Respiratory function Scientific Concepts Treatment Outcome Vital Capacity - drug effects Weight Gain - drug effects
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