High TIMM17A expression is associated with adverse pathological and clinical outcomes in human breast cancer

Background Mitochondrial dysfunction can be associated with genomic instability and has been implicated in the pathogenesis of several human malignancies, including breast cancer (BC). The mitochondrial protein, translocase of inner mitochondrial membrane 17 homolog A (TIMM17A) contributes to a pre-...

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Veröffentlicht in:	Breast cancer (Tokyo, Japan) Japan), 2012-04, Vol.19 (2), p.153-160
Hauptverfasser:	Salhab, Mohamed, Patani, Neill, Jiang, Wen, Mokbel, Kefah
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Breast - metabolism Breast - pathology Breast cancer Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - pathology Cancer Research Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - mortality Carcinoma, Ductal, Breast - secondary Carcinoma, Lobular - genetics Carcinoma, Lobular - mortality Carcinoma, Lobular - secondary Carcinoma, Medullary - genetics Carcinoma, Medullary - mortality Carcinoma, Medullary - secondary Comparative analysis Estrogen Female Genetic transcription Humans Medical colleges Medicine Medicine & Public Health Mitochondrial Membrane Transport Proteins - genetics Neoplasm Grading Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Staging Oncology Original Article Patient outcomes Prognosis Real-Time Polymerase Chain Reaction RNA RNA, Messenger - genetics Surgery Surgical Oncology Survival Rate
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