Randomized controlled trial of the effectiveness of a soybean-maize-sorghum―based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo
Evidence of the effectiveness of lipid-based ready-to-use complementary foods (RUCF) at improving linear growth among infants aged 6-12 mo is scarce, and further work is warranted. The objective was to assess the effectiveness of a fortified soybean-maize-sorghum RUCF paste compared with a fortified...
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| Veröffentlicht in: | The American journal of clinical nutrition 2012-05, Vol.95 (5), p.1157-1164 |
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| creator | BISIMWA, Ghislain OWINO, Victor O BAHWERE, Paluku DRAMAIX, Michele DONNEN, Philippe DIBARI, Filippo COLLINS, Steve |
| description | Evidence of the effectiveness of lipid-based ready-to-use complementary foods (RUCF) at improving linear growth among infants aged 6-12 mo is scarce, and further work is warranted.
The objective was to assess the effectiveness of a fortified soybean-maize-sorghum RUCF paste compared with a fortified corn soy blend (UNIMIX) porridge on the prevalence of underweight and stunting among infants in South Kivu Province, Democratic Republic of Congo.
Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 691) or UNIMIX (n = 692) for 6 mo. In addition to admission and monthly anthropometric measurements, hemoglobin, triglyceride, and cholesterol were measured at enrollment and at the end of the study.
No significant differences in the prevalence of stunting (RUCF: 48.6%; UNIMIX: 46.4%; P = 0.31), the prevalence of underweight (RUCF: 20.4%; UNIMIX: 18.2%; P = 0.42), or weight gain (RUCF: 1.2 ± 0.7 kg; UNIMIX: 1.3 ± 0.7 kg; P = 0.08) were found. A small but statistically significant difference in length gain (RUCF: 5.2 ± 2.0; UNIMIX: 5.4 ± 2.0; P = 0.03) was found. No significant differences in the concentrations of hemoglobin, serum triglyceride, and serum cholesterol were found between the 2 groups.
No significant differences were found between the RUCF and UNIMIX in the reduction of the prevalence of stunting and underweight at 12 mo of age among rural Congolese infants. This trial was registered at controlled-trials.com as ISRCTN20267635. |
| doi_str_mv | 10.3945/ajcn.111.028704 |
| format | Article |
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The objective was to assess the effectiveness of a fortified soybean-maize-sorghum RUCF paste compared with a fortified corn soy blend (UNIMIX) porridge on the prevalence of underweight and stunting among infants in South Kivu Province, Democratic Republic of Congo.
Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 691) or UNIMIX (n = 692) for 6 mo. In addition to admission and monthly anthropometric measurements, hemoglobin, triglyceride, and cholesterol were measured at enrollment and at the end of the study.
No significant differences in the prevalence of stunting (RUCF: 48.6%; UNIMIX: 46.4%; P = 0.31), the prevalence of underweight (RUCF: 20.4%; UNIMIX: 18.2%; P = 0.42), or weight gain (RUCF: 1.2 ± 0.7 kg; UNIMIX: 1.3 ± 0.7 kg; P = 0.08) were found. A small but statistically significant difference in length gain (RUCF: 5.2 ± 2.0; UNIMIX: 5.4 ± 2.0; P = 0.03) was found. No significant differences in the concentrations of hemoglobin, serum triglyceride, and serum cholesterol were found between the 2 groups.
No significant differences were found between the RUCF and UNIMIX in the reduction of the prevalence of stunting and underweight at 12 mo of age among rural Congolese infants. This trial was registered at controlled-trials.com as ISRCTN20267635.</description><identifier>ISSN: 0002-9165</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.3945/ajcn.111.028704</identifier><identifier>PMID: 22492382</identifier><identifier>CODEN: AJCNAC</identifier><language>eng</language><publisher>Bethesda, MD: American Society for Nutrition</publisher><subject>Babies ; Biological and medical sciences ; Cross-Over Studies ; Democratic Republic of the Congo ; Edible Grain - chemistry ; Energy Intake ; Feeding. Feeding behavior ; Female ; Food Handling ; Food, Fortified ; Fundamental and applied biological sciences. Psychology ; Glycine max - chemistry ; Hemoglobin ; Humans ; Infant ; Infant Food ; Infant Nutritional Physiological Phenomena ; Lipids ; Male ; Malnutrition ; Micronutrients - administration & dosage ; Prospective Studies ; Sorghum - chemistry ; Soybeans ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Weight Gain ; Zea mays - chemistry</subject><ispartof>The American journal of clinical nutrition, 2012-05, Vol.95 (5), p.1157-1164</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright American Society for Clinical Nutrition, Inc. May 1, 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-57490c3e220828fd4b78996b257f378963a232b8df72d3fab75c922b9fda05353</citedby><cites>FETCH-LOGICAL-c396t-57490c3e220828fd4b78996b257f378963a232b8df72d3fab75c922b9fda05353</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25834884$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22492382$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BISIMWA, Ghislain</creatorcontrib><creatorcontrib>OWINO, Victor O</creatorcontrib><creatorcontrib>BAHWERE, Paluku</creatorcontrib><creatorcontrib>DRAMAIX, Michele</creatorcontrib><creatorcontrib>DONNEN, Philippe</creatorcontrib><creatorcontrib>DIBARI, Filippo</creatorcontrib><creatorcontrib>COLLINS, Steve</creatorcontrib><title>Randomized controlled trial of the effectiveness of a soybean-maize-sorghum―based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo</title><title>The American journal of clinical nutrition</title><addtitle>Am J Clin Nutr</addtitle><description>Evidence of the effectiveness of lipid-based ready-to-use complementary foods (RUCF) at improving linear growth among infants aged 6-12 mo is scarce, and further work is warranted.
The objective was to assess the effectiveness of a fortified soybean-maize-sorghum RUCF paste compared with a fortified corn soy blend (UNIMIX) porridge on the prevalence of underweight and stunting among infants in South Kivu Province, Democratic Republic of Congo.
Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 691) or UNIMIX (n = 692) for 6 mo. In addition to admission and monthly anthropometric measurements, hemoglobin, triglyceride, and cholesterol were measured at enrollment and at the end of the study.
No significant differences in the prevalence of stunting (RUCF: 48.6%; UNIMIX: 46.4%; P = 0.31), the prevalence of underweight (RUCF: 20.4%; UNIMIX: 18.2%; P = 0.42), or weight gain (RUCF: 1.2 ± 0.7 kg; UNIMIX: 1.3 ± 0.7 kg; P = 0.08) were found. A small but statistically significant difference in length gain (RUCF: 5.2 ± 2.0; UNIMIX: 5.4 ± 2.0; P = 0.03) was found. No significant differences in the concentrations of hemoglobin, serum triglyceride, and serum cholesterol were found between the 2 groups.
No significant differences were found between the RUCF and UNIMIX in the reduction of the prevalence of stunting and underweight at 12 mo of age among rural Congolese infants. This trial was registered at controlled-trials.com as ISRCTN20267635.</description><subject>Babies</subject><subject>Biological and medical sciences</subject><subject>Cross-Over Studies</subject><subject>Democratic Republic of the Congo</subject><subject>Edible Grain - chemistry</subject><subject>Energy Intake</subject><subject>Feeding. Feeding behavior</subject><subject>Female</subject><subject>Food Handling</subject><subject>Food, Fortified</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glycine max - chemistry</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant Food</subject><subject>Infant Nutritional Physiological Phenomena</subject><subject>Lipids</subject><subject>Male</subject><subject>Malnutrition</subject><subject>Micronutrients - administration & dosage</subject><subject>Prospective Studies</subject><subject>Sorghum - chemistry</subject><subject>Soybeans</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Weight Gain</subject><subject>Zea mays - chemistry</subject><issn>0002-9165</issn><issn>1938-3207</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkc2KFDEUhYMoTs_o2p0ERJiF1ZOf-kmWQ_uLA8Ko6-JW6qa7mqqkTVIj7cqX8FV8IJ_ENN0quMrJ5Tsn4R5CnnC2lLqsrmBr3JJzvmRCNay8RxZcS1VIwZr7ZMEYE4XmdXVGzmPcMsZFqeqH5EyIUgupxIL8vAXX-2n4hj013qXgxzHLFAYYqbc0bZCitWjScIcOYzwMgUa_7xBcMUF2FtGH9Waefn3_0UHM7oDQ74vkizliTp12I07oEoQ9td73dAcxIfWODs6CS3Qd_Ne0yTf60c9ZvB_u5hf0JU7eBEiDobe4m7sxi_z4yru1f0QeWBgjPj6dF-Tz61efVm-Lmw9v3q2ubwojdZ2Kqik1MxKFYEoo25ddo7SuO1E1VmZZSxBSdKq3jeilha6pjBai07YHVslKXpDLY-4u-C8zxtROQzQ4juDQz7HljGkudCNlRp_9h279HFz-XaY4E5WWrMnU1ZEywccY0La7MEx5MxlqD5W2h0rbXGl7rDQ7np5y527C_i__p8MMPD8BEA2MNoAzQ_zHVUqWSpXyN4rsrUU</recordid><startdate>20120501</startdate><enddate>20120501</enddate><creator>BISIMWA, Ghislain</creator><creator>OWINO, Victor O</creator><creator>BAHWERE, Paluku</creator><creator>DRAMAIX, Michele</creator><creator>DONNEN, Philippe</creator><creator>DIBARI, Filippo</creator><creator>COLLINS, Steve</creator><general>American Society for Nutrition</general><general>American Society for Clinical Nutrition, Inc</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T7</scope><scope>7TS</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20120501</creationdate><title>Randomized controlled trial of the effectiveness of a soybean-maize-sorghum―based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo</title><author>BISIMWA, Ghislain ; OWINO, Victor O ; BAHWERE, Paluku ; DRAMAIX, Michele ; DONNEN, Philippe ; DIBARI, Filippo ; COLLINS, Steve</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-57490c3e220828fd4b78996b257f378963a232b8df72d3fab75c922b9fda05353</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Babies</topic><topic>Biological and medical sciences</topic><topic>Cross-Over Studies</topic><topic>Democratic Republic of the Congo</topic><topic>Edible Grain - chemistry</topic><topic>Energy Intake</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Food Handling</topic><topic>Food, Fortified</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glycine max - chemistry</topic><topic>Hemoglobin</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant Food</topic><topic>Infant Nutritional Physiological Phenomena</topic><topic>Lipids</topic><topic>Male</topic><topic>Malnutrition</topic><topic>Micronutrients - administration & dosage</topic><topic>Prospective Studies</topic><topic>Sorghum - chemistry</topic><topic>Soybeans</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Weight Gain</topic><topic>Zea mays - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BISIMWA, Ghislain</creatorcontrib><creatorcontrib>OWINO, Victor O</creatorcontrib><creatorcontrib>BAHWERE, Paluku</creatorcontrib><creatorcontrib>DRAMAIX, Michele</creatorcontrib><creatorcontrib>DONNEN, Philippe</creatorcontrib><creatorcontrib>DIBARI, Filippo</creatorcontrib><creatorcontrib>COLLINS, Steve</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BISIMWA, Ghislain</au><au>OWINO, Victor O</au><au>BAHWERE, Paluku</au><au>DRAMAIX, Michele</au><au>DONNEN, Philippe</au><au>DIBARI, Filippo</au><au>COLLINS, Steve</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Randomized controlled trial of the effectiveness of a soybean-maize-sorghum―based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo</atitle><jtitle>The American journal of clinical nutrition</jtitle><addtitle>Am J Clin Nutr</addtitle><date>2012-05-01</date><risdate>2012</risdate><volume>95</volume><issue>5</issue><spage>1157</spage><epage>1164</epage><pages>1157-1164</pages><issn>0002-9165</issn><eissn>1938-3207</eissn><coden>AJCNAC</coden><abstract>Evidence of the effectiveness of lipid-based ready-to-use complementary foods (RUCF) at improving linear growth among infants aged 6-12 mo is scarce, and further work is warranted.
The objective was to assess the effectiveness of a fortified soybean-maize-sorghum RUCF paste compared with a fortified corn soy blend (UNIMIX) porridge on the prevalence of underweight and stunting among infants in South Kivu Province, Democratic Republic of Congo.
Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 691) or UNIMIX (n = 692) for 6 mo. In addition to admission and monthly anthropometric measurements, hemoglobin, triglyceride, and cholesterol were measured at enrollment and at the end of the study.
No significant differences in the prevalence of stunting (RUCF: 48.6%; UNIMIX: 46.4%; P = 0.31), the prevalence of underweight (RUCF: 20.4%; UNIMIX: 18.2%; P = 0.42), or weight gain (RUCF: 1.2 ± 0.7 kg; UNIMIX: 1.3 ± 0.7 kg; P = 0.08) were found. A small but statistically significant difference in length gain (RUCF: 5.2 ± 2.0; UNIMIX: 5.4 ± 2.0; P = 0.03) was found. No significant differences in the concentrations of hemoglobin, serum triglyceride, and serum cholesterol were found between the 2 groups.
No significant differences were found between the RUCF and UNIMIX in the reduction of the prevalence of stunting and underweight at 12 mo of age among rural Congolese infants. This trial was registered at controlled-trials.com as ISRCTN20267635.</abstract><cop>Bethesda, MD</cop><pub>American Society for Nutrition</pub><pmid>22492382</pmid><doi>10.3945/ajcn.111.028704</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Babies Biological and medical sciences Cross-Over Studies Democratic Republic of the Congo Edible Grain - chemistry Energy Intake Feeding. Feeding behavior Female Food Handling Food, Fortified Fundamental and applied biological sciences. Psychology Glycine max - chemistry Hemoglobin Humans Infant Infant Food Infant Nutritional Physiological Phenomena Lipids Male Malnutrition Micronutrients - administration & dosage Prospective Studies Sorghum - chemistry Soybeans Vertebrates: anatomy and physiology, studies on body, several organs or systems Weight Gain Zea mays - chemistry |
| title | Randomized controlled trial of the effectiveness of a soybean-maize-sorghum―based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo |
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