Reduced expression of DNA repair genes (XRCC1, XPD, and OGG1) in squamous cell carcinoma of head and neck in North India

Squamous cell carcinoma of head and neck (SCCHN) is the sixth most common cancer globally, and in India, it accounts for 30% of all cancer cases. Epidemiological studies have shown a positive association between defective DNA repair capacity and SCCHN. The underlying mechanism of their involvement i...

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Veröffentlicht in:	Tumor biology 2012-02, Vol.33 (1), p.111-119
Hauptverfasser:	Kumar, Anil, Pant, Mohan Chand, Singh, Hirdya Shanker, Khandelwal, Shashi
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxyguanine Adult Age Aged alcohols Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma, Squamous Cell - genetics DNA adducts DNA glycosylase DNA Glycosylases - genetics DNA repair DNA Repair - genetics DNA-Binding Proteins - genetics Epidemiology Gene expression Gene Expression Regulation, Neoplastic Head & neck cancer Head and neck cancer Head and Neck Neoplasms - genetics Humans Male Middle Aged OGG1 protein Regression analysis Research Article Smoking squamous cell carcinoma Statistical analysis Tumors X-ray Repair Cross Complementing Protein 1 Xeroderma pigmentosum Xeroderma Pigmentosum Group D Protein - genetics XPD protein XRCC1 protein
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