High-dose esomeprazole is required for intraesophageal acid control in gastroesophageal reflux disease patients with hiatus hernia

Background and Aim: The aim of this study was to assess whether the efficacy of proton pump inhibitors (PPI) therapy at a standard dose in esophageal acid control is affected by the presence of hiatus hernia in Chinese gastroesophageal reflux disease patients, and whether a higher dose of PPI is re...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2012-05, Vol.27 (5), p.893-898
Hauptverfasser:	Peng, Sui, Xiao, Ying-Lian, Cui, Yi, Lin, Jin-Kun, Zhang, Ning, Hu, Pin-Jin, Chen, Min-Hu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Asian Continental Ancestry Group Chi-Square Distribution China esomeprazole Esomeprazole - administration & dosage esophageal acid control Esophageal pH Monitoring Female Gastroesophageal Reflux - complications Gastroesophageal Reflux - drug therapy gastroesophageal reflux disease Gastroscopy Hernia, Hiatal - complications hiatus hernia Humans Male Middle Aged Proton Pump Inhibitors - administration & dosage Statistics, Nonparametric Time Factors
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