Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer

Over the last two decades, extensive research on plant-based medicinal compounds has revealed exciting and important pharmacological properties and activities of triterpenoids. Fruits, vegetables, cereals, pulses, herbs and medicinal plants are all considered to be biological sources of these triter...

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Veröffentlicht in:	Cancer letters 2012-07, Vol.320 (2), p.158-170
Hauptverfasser:	Shanmugam, Muthu K, Nguyen, An H, Kumar, Alan P, Tan, Benny K.H, Sethi, Gautam
Format:	Artikel
Sprache:	eng
Schlagworte:	angiogenesis anticarcinogenic activity Anticarcinogenic Agents - pharmacology Apoptosis Apoptosis - drug effects Apoptosis Regulatory Proteins - pharmacology Cancer cell proliferation Cell Proliferation - drug effects chemokines chemoprevention Colorectal cancer enzymes fruits grains Hematology, Oncology and Palliative Medicine Herbal medicine Humans inflammation Inflammation - prevention & control Kinases medicinal plants Metastasis Molecular Targeted Therapy Neoplasm Metastasis - prevention & control neoplasms Neoplasms - drug therapy Neoplasms - pathology Neoplasms - prevention & control oncogenes oxygen Pentacyclic Triterpenes - pharmacology physicochemical properties Proliferation Prostate cancer proteins radiation resistance Signal Transduction Skin cancer therapeutics transcription (genetics) transcription factors Triterpenes - chemistry Triterpenes - pharmacology Triterpenoids vegetables
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