Increased risk of dehiscence after tricuspid valve repair with rigid annuloplasty rings

Objectives Surgical management of tricuspid valve regurgitation mainly consists of tricuspid valve annuloplasty, usually performed with implantation of a rigid ring or a flexible band. Methods We performed a retrospective analysis on 820 patients who underwent tricuspid valve repair between March 20...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2012-05, Vol.143 (5), p.1050-1055
Hauptverfasser: Pfannmüller, Bettina, MD, Doenst, Torsten, MD, PHD, Eberhardt, Katja, BS, Seeburger, Jörg, MD, Borger, Michael A., MD, PhD, Mohr, Friedrich W., MD, PhD
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container_end_page 1055
container_issue 5
container_start_page 1050
container_title The Journal of thoracic and cardiovascular surgery
container_volume 143
creator Pfannmüller, Bettina, MD
Doenst, Torsten, MD, PHD
Eberhardt, Katja, BS
Seeburger, Jörg, MD
Borger, Michael A., MD, PhD
Mohr, Friedrich W., MD, PhD
description Objectives Surgical management of tricuspid valve regurgitation mainly consists of tricuspid valve annuloplasty, usually performed with implantation of a rigid ring or a flexible band. Methods We performed a retrospective analysis on 820 patients who underwent tricuspid valve repair between March 2002 and July 2009 with either a flexible Cosgrove-Edwards band (n = 415; Edwards Lifesciences LLC, Irvine, Calif) or a rigid Carpentier-Edwards Classic annuloplasty ring (n = 405; Edwards Lifesciences). Mean patient age was 69.2 ± 9.5 years, 54.1% were female, and average logistic EuroSCORE was 13.3% ± 12.5%. Concomitant procedures were performed in 94.6% of patients (mitral valve surgery, 80.6%; aortic valve surgery, 28.2%; coronary artery bypass grafting, 24.5%; atrial fibrillation ablation, 44.5%). One fifth of the operations were reoperative procedures. Follow-up was 94% complete, with mean duration of 21.0 ± 19.0 months. Results Thirty-day mortality was 10.1% (Cosgrove-Edwards, 11.9%; Carpentier-Edwards, 8.4%), and 5-year survival was 62.4% (Carpentier-Edwards, 64.7%; Cosgrove-Edwards, 60.3%). Postoperative echocardiography showed significant improvement in tricuspid valve function, with reduction in tricuspid regurgitation grade from 2.3 ± 0.7 to 0.7 ± 0.7, and no differences between groups. Use of a Carpentier-Edwards ring, however, was associated with significantly higher risk of dehiscence (Carpentier-Edwards, 8.7%; Cosgrove-Edwards, 0.9%; P  
doi_str_mv 10.1016/j.jtcvs.2011.06.019
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Methods We performed a retrospective analysis on 820 patients who underwent tricuspid valve repair between March 2002 and July 2009 with either a flexible Cosgrove-Edwards band (n = 415; Edwards Lifesciences LLC, Irvine, Calif) or a rigid Carpentier-Edwards Classic annuloplasty ring (n = 405; Edwards Lifesciences). Mean patient age was 69.2 ± 9.5 years, 54.1% were female, and average logistic EuroSCORE was 13.3% ± 12.5%. Concomitant procedures were performed in 94.6% of patients (mitral valve surgery, 80.6%; aortic valve surgery, 28.2%; coronary artery bypass grafting, 24.5%; atrial fibrillation ablation, 44.5%). One fifth of the operations were reoperative procedures. Follow-up was 94% complete, with mean duration of 21.0 ± 19.0 months. Results Thirty-day mortality was 10.1% (Cosgrove-Edwards, 11.9%; Carpentier-Edwards, 8.4%), and 5-year survival was 62.4% (Carpentier-Edwards, 64.7%; Cosgrove-Edwards, 60.3%). Postoperative echocardiography showed significant improvement in tricuspid valve function, with reduction in tricuspid regurgitation grade from 2.3 ± 0.7 to 0.7 ± 0.7, and no differences between groups. Use of a Carpentier-Edwards ring, however, was associated with significantly higher risk of dehiscence (Carpentier-Edwards, 8.7%; Cosgrove-Edwards, 0.9%; P  &lt; .001), almost exclusively at the septal leaflet portion of the annulus. Multivariate analysis identified annuloplasty type as independently predicting ring dehiscence (odds ratio, 10.7; 95% confidence interval, 3.2–36.5; P  &lt; .001). Patients with annuloplasty dehiscence had more residual tricuspid regurgitation on predischarge echocardiography than did patients without dehiscence (1.4 ± 0.63 vs 0.7 ± 0.6; P  &lt; .001). Ten patients underwent reoperation for recurrent tricuspid regurgitation, 4 with ring dehiscence. Five-year freedom from reoperation was 95.3% (Cosgrove-Edwards, 97.7%; Carpentier-Edwards, 92.3%). Conclusions Although both rigid and flexible systems provide acceptable early tricuspid valve repair results, use of a rigid ring increases risk of subsequent ring dehiscence.</description><identifier>ISSN: 0022-5223</identifier><identifier>EISSN: 1097-685X</identifier><identifier>DOI: 10.1016/j.jtcvs.2011.06.019</identifier><identifier>PMID: 21798563</identifier><identifier>CODEN: JTCSAQ</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Cardiac Valve Annuloplasty - adverse effects ; Cardiac Valve Annuloplasty - instrumentation ; Cardiology. Vascular system ; Cardiothoracic Surgery ; Female ; Germany ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation - adverse effects ; Heart Valve Prosthesis Implantation - instrumentation ; Humans ; Kaplan-Meier Estimate ; Male ; Medical sciences ; Middle Aged ; Odds Ratio ; Pneumology ; Prosthesis Design ; Reoperation ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Surgical Wound Dehiscence - diagnostic imaging ; Surgical Wound Dehiscence - etiology ; Surgical Wound Dehiscence - mortality ; Surgical Wound Dehiscence - surgery ; Time Factors ; Treatment Outcome ; Tricuspid Valve - diagnostic imaging ; Tricuspid Valve - surgery ; Tricuspid Valve Insufficiency - diagnostic imaging ; Tricuspid Valve Insufficiency - mortality ; Tricuspid Valve Insufficiency - surgery ; Ultrasonography</subject><ispartof>The Journal of thoracic and cardiovascular surgery, 2012-05, Vol.143 (5), p.1050-1055</ispartof><rights>The American Association for Thoracic Surgery</rights><rights>2012 The American Association for Thoracic Surgery</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c489t-8b0ffe6505ce4b5d1e67e1f1b939bf958a0422e0483616f250f57a0f566c42de3</citedby><cites>FETCH-LOGICAL-c489t-8b0ffe6505ce4b5d1e67e1f1b939bf958a0422e0483616f250f57a0f566c42de3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jtcvs.2011.06.019$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=25878082$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21798563$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pfannmüller, Bettina, MD</creatorcontrib><creatorcontrib>Doenst, Torsten, MD, PHD</creatorcontrib><creatorcontrib>Eberhardt, Katja, BS</creatorcontrib><creatorcontrib>Seeburger, Jörg, MD</creatorcontrib><creatorcontrib>Borger, Michael A., MD, PhD</creatorcontrib><creatorcontrib>Mohr, Friedrich W., MD, PhD</creatorcontrib><title>Increased risk of dehiscence after tricuspid valve repair with rigid annuloplasty rings</title><title>The Journal of thoracic and cardiovascular surgery</title><addtitle>J Thorac Cardiovasc Surg</addtitle><description>Objectives Surgical management of tricuspid valve regurgitation mainly consists of tricuspid valve annuloplasty, usually performed with implantation of a rigid ring or a flexible band. Methods We performed a retrospective analysis on 820 patients who underwent tricuspid valve repair between March 2002 and July 2009 with either a flexible Cosgrove-Edwards band (n = 415; Edwards Lifesciences LLC, Irvine, Calif) or a rigid Carpentier-Edwards Classic annuloplasty ring (n = 405; Edwards Lifesciences). Mean patient age was 69.2 ± 9.5 years, 54.1% were female, and average logistic EuroSCORE was 13.3% ± 12.5%. Concomitant procedures were performed in 94.6% of patients (mitral valve surgery, 80.6%; aortic valve surgery, 28.2%; coronary artery bypass grafting, 24.5%; atrial fibrillation ablation, 44.5%). One fifth of the operations were reoperative procedures. Follow-up was 94% complete, with mean duration of 21.0 ± 19.0 months. Results Thirty-day mortality was 10.1% (Cosgrove-Edwards, 11.9%; Carpentier-Edwards, 8.4%), and 5-year survival was 62.4% (Carpentier-Edwards, 64.7%; Cosgrove-Edwards, 60.3%). Postoperative echocardiography showed significant improvement in tricuspid valve function, with reduction in tricuspid regurgitation grade from 2.3 ± 0.7 to 0.7 ± 0.7, and no differences between groups. Use of a Carpentier-Edwards ring, however, was associated with significantly higher risk of dehiscence (Carpentier-Edwards, 8.7%; Cosgrove-Edwards, 0.9%; P  &lt; .001), almost exclusively at the septal leaflet portion of the annulus. Multivariate analysis identified annuloplasty type as independently predicting ring dehiscence (odds ratio, 10.7; 95% confidence interval, 3.2–36.5; P  &lt; .001). Patients with annuloplasty dehiscence had more residual tricuspid regurgitation on predischarge echocardiography than did patients without dehiscence (1.4 ± 0.63 vs 0.7 ± 0.6; P  &lt; .001). Ten patients underwent reoperation for recurrent tricuspid regurgitation, 4 with ring dehiscence. Five-year freedom from reoperation was 95.3% (Cosgrove-Edwards, 97.7%; Carpentier-Edwards, 92.3%). Conclusions Although both rigid and flexible systems provide acceptable early tricuspid valve repair results, use of a rigid ring increases risk of subsequent ring dehiscence.</description><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cardiac Valve Annuloplasty - adverse effects</subject><subject>Cardiac Valve Annuloplasty - instrumentation</subject><subject>Cardiology. Vascular system</subject><subject>Cardiothoracic Surgery</subject><subject>Female</subject><subject>Germany</subject><subject>Heart Valve Prosthesis</subject><subject>Heart Valve Prosthesis Implantation - adverse effects</subject><subject>Heart Valve Prosthesis Implantation - instrumentation</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Odds Ratio</subject><subject>Pneumology</subject><subject>Prosthesis Design</subject><subject>Reoperation</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Surgical Wound Dehiscence - diagnostic imaging</subject><subject>Surgical Wound Dehiscence - etiology</subject><subject>Surgical Wound Dehiscence - mortality</subject><subject>Surgical Wound Dehiscence - surgery</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Tricuspid Valve - diagnostic imaging</subject><subject>Tricuspid Valve - surgery</subject><subject>Tricuspid Valve Insufficiency - diagnostic imaging</subject><subject>Tricuspid Valve Insufficiency - mortality</subject><subject>Tricuspid Valve Insufficiency - surgery</subject><subject>Ultrasonography</subject><issn>0022-5223</issn><issn>1097-685X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUGL1TAQx4Mo7tvVTyBIL4KX1knapOlBQRZXFxY8qOgtpOlkN92-9plpn7xvb-p7KnjxksDw-2cmv2HsGYeCA1ev-qKf3Z4KAZwXoArgzQO24dDUudLy20O2ARAil0KUZ-ycqAeAOkGP2ZngdaOlKjfs6_XoIlrCLouB7rPJZx3eBXI4OsysnzFmcwxuoV3osr0d9phF3NkQsx9hvkuh21S347gM026wNB9SabylJ-yRtwPh09N9wb5cvft8-SG_-fj--vLtTe4q3cy5bsF7VBKkw6qVHUdVI_e8bcqm9Y3UFiohECpdKq68kOBlbdOhlKtEh-UFe3l8dxen7wvSbLbr8MNgR5wWMhzSj6VWskxoeURdnIgierOLYWvjIUFmNWp688uoWY0aUCZFU-r5qcHSbrH7k_mtMAEvToAlZwcf7egC_eWkrjVokbjXRw6Tjn3AaMiF1XIXIrrZdFP4zyBv_sm7IYwhtbzHA1I_LXFMpg03JAyYT-vy193zpEBp0ZQ_ASNLqsg</recordid><startdate>20120501</startdate><enddate>20120501</enddate><creator>Pfannmüller, Bettina, MD</creator><creator>Doenst, Torsten, MD, PHD</creator><creator>Eberhardt, Katja, BS</creator><creator>Seeburger, Jörg, MD</creator><creator>Borger, Michael A., MD, PhD</creator><creator>Mohr, Friedrich W., MD, PhD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120501</creationdate><title>Increased risk of dehiscence after tricuspid valve repair with rigid annuloplasty rings</title><author>Pfannmüller, Bettina, MD ; Doenst, Torsten, MD, PHD ; Eberhardt, Katja, BS ; Seeburger, Jörg, MD ; Borger, Michael A., MD, PhD ; Mohr, Friedrich W., MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c489t-8b0ffe6505ce4b5d1e67e1f1b939bf958a0422e0483616f250f57a0f566c42de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Cardiac Valve Annuloplasty - adverse effects</topic><topic>Cardiac Valve Annuloplasty - instrumentation</topic><topic>Cardiology. Vascular system</topic><topic>Cardiothoracic Surgery</topic><topic>Female</topic><topic>Germany</topic><topic>Heart Valve Prosthesis</topic><topic>Heart Valve Prosthesis Implantation - adverse effects</topic><topic>Heart Valve Prosthesis Implantation - instrumentation</topic><topic>Humans</topic><topic>Kaplan-Meier Estimate</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Odds Ratio</topic><topic>Pneumology</topic><topic>Prosthesis Design</topic><topic>Reoperation</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Surgical Wound Dehiscence - diagnostic imaging</topic><topic>Surgical Wound Dehiscence - etiology</topic><topic>Surgical Wound Dehiscence - mortality</topic><topic>Surgical Wound Dehiscence - surgery</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Tricuspid Valve - diagnostic imaging</topic><topic>Tricuspid Valve - surgery</topic><topic>Tricuspid Valve Insufficiency - diagnostic imaging</topic><topic>Tricuspid Valve Insufficiency - mortality</topic><topic>Tricuspid Valve Insufficiency - surgery</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pfannmüller, Bettina, MD</creatorcontrib><creatorcontrib>Doenst, Torsten, MD, PHD</creatorcontrib><creatorcontrib>Eberhardt, Katja, BS</creatorcontrib><creatorcontrib>Seeburger, Jörg, MD</creatorcontrib><creatorcontrib>Borger, Michael A., MD, PhD</creatorcontrib><creatorcontrib>Mohr, Friedrich W., MD, PhD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pfannmüller, Bettina, MD</au><au>Doenst, Torsten, MD, PHD</au><au>Eberhardt, Katja, BS</au><au>Seeburger, Jörg, MD</au><au>Borger, Michael A., MD, PhD</au><au>Mohr, Friedrich W., MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased risk of dehiscence after tricuspid valve repair with rigid annuloplasty rings</atitle><jtitle>The Journal of thoracic and cardiovascular surgery</jtitle><addtitle>J Thorac Cardiovasc Surg</addtitle><date>2012-05-01</date><risdate>2012</risdate><volume>143</volume><issue>5</issue><spage>1050</spage><epage>1055</epage><pages>1050-1055</pages><issn>0022-5223</issn><eissn>1097-685X</eissn><coden>JTCSAQ</coden><abstract>Objectives Surgical management of tricuspid valve regurgitation mainly consists of tricuspid valve annuloplasty, usually performed with implantation of a rigid ring or a flexible band. Methods We performed a retrospective analysis on 820 patients who underwent tricuspid valve repair between March 2002 and July 2009 with either a flexible Cosgrove-Edwards band (n = 415; Edwards Lifesciences LLC, Irvine, Calif) or a rigid Carpentier-Edwards Classic annuloplasty ring (n = 405; Edwards Lifesciences). Mean patient age was 69.2 ± 9.5 years, 54.1% were female, and average logistic EuroSCORE was 13.3% ± 12.5%. Concomitant procedures were performed in 94.6% of patients (mitral valve surgery, 80.6%; aortic valve surgery, 28.2%; coronary artery bypass grafting, 24.5%; atrial fibrillation ablation, 44.5%). One fifth of the operations were reoperative procedures. Follow-up was 94% complete, with mean duration of 21.0 ± 19.0 months. Results Thirty-day mortality was 10.1% (Cosgrove-Edwards, 11.9%; Carpentier-Edwards, 8.4%), and 5-year survival was 62.4% (Carpentier-Edwards, 64.7%; Cosgrove-Edwards, 60.3%). Postoperative echocardiography showed significant improvement in tricuspid valve function, with reduction in tricuspid regurgitation grade from 2.3 ± 0.7 to 0.7 ± 0.7, and no differences between groups. Use of a Carpentier-Edwards ring, however, was associated with significantly higher risk of dehiscence (Carpentier-Edwards, 8.7%; Cosgrove-Edwards, 0.9%; P  &lt; .001), almost exclusively at the septal leaflet portion of the annulus. Multivariate analysis identified annuloplasty type as independently predicting ring dehiscence (odds ratio, 10.7; 95% confidence interval, 3.2–36.5; P  &lt; .001). Patients with annuloplasty dehiscence had more residual tricuspid regurgitation on predischarge echocardiography than did patients without dehiscence (1.4 ± 0.63 vs 0.7 ± 0.6; P  &lt; .001). Ten patients underwent reoperation for recurrent tricuspid regurgitation, 4 with ring dehiscence. Five-year freedom from reoperation was 95.3% (Cosgrove-Edwards, 97.7%; Carpentier-Edwards, 92.3%). Conclusions Although both rigid and flexible systems provide acceptable early tricuspid valve repair results, use of a rigid ring increases risk of subsequent ring dehiscence.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>21798563</pmid><doi>10.1016/j.jtcvs.2011.06.019</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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subjects Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Cardiac Valve Annuloplasty - adverse effects
Cardiac Valve Annuloplasty - instrumentation
Cardiology. Vascular system
Cardiothoracic Surgery
Female
Germany
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation - adverse effects
Heart Valve Prosthesis Implantation - instrumentation
Humans
Kaplan-Meier Estimate
Male
Medical sciences
Middle Aged
Odds Ratio
Pneumology
Prosthesis Design
Reoperation
Retrospective Studies
Risk Assessment
Risk Factors
Surgical Wound Dehiscence - diagnostic imaging
Surgical Wound Dehiscence - etiology
Surgical Wound Dehiscence - mortality
Surgical Wound Dehiscence - surgery
Time Factors
Treatment Outcome
Tricuspid Valve - diagnostic imaging
Tricuspid Valve - surgery
Tricuspid Valve Insufficiency - diagnostic imaging
Tricuspid Valve Insufficiency - mortality
Tricuspid Valve Insufficiency - surgery
Ultrasonography
title Increased risk of dehiscence after tricuspid valve repair with rigid annuloplasty rings
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