Effect of l-NAME, an inhibitor of nitric oxide synthesis, on plasma levels of IL-6, IL-8, TNF[alpha] and nitrite/nitrate in human septic shock

Objectives: We tested the effects of N^sup G^-nitro-L-arginine methyl ester (l-NAME), an inhibitor of nitric oxide (NO) synthesis, on plasma levels of interleukin (IL) IL-6, IL-8, tumor necrosis factor-alpha (TNFα) and nitrite/nitrate (NO^sub 2^^sup -^/NO^sub 3^^sup -^) in patients with severe septi...

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