Prostate-specific membrane antigen as a potential novel vascular target for treatment of glioblastoma multiforme

Prostate-specific membrane antigen (PSMA) is expressed in endothelium of vessels in malignant solid tumors but not in normal vessels. To examine whether neovasculature of glioblastoma multiforme (GBM) expresses PSMA. Design.-After institutional review board approval at Memorial Sloan-Kettering Cance...

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Veröffentlicht in:	Archives of pathology & laboratory medicine (1976) 2011-11, Vol.135 (11), p.1486-1489
Hauptverfasser:	Wernicke, A Gabriella, Edgar, Mark A, Lavi, Ehud, Liu, He, Salerno, Pamela, Bander, Neil H, Gutin, Philip H
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Antigens, Surface - metabolism Brain cancer Brain Neoplasms - metabolism Endothelium Formaldehyde Glioblastoma - metabolism Glioblastoma multiforme Glutamate Carboxypeptidase II - metabolism Humans Hypoxia Immunoglobulins Immunohistochemistry Neovascularization, Pathologic - metabolism Prostate Review boards Tumors Vascular endothelial growth factor
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