Intestinal CX^sub 3^C chemokine receptor 1^sup high^ (CX^sub 3^CR1^sup high^) myeloid cells prevent T-cell-dependent colitis

Adequate activation of CD4+ T lymphocytes is essential for host defense against invading pathogens; however, exaggerated activity of effector CD4+ T cells induces tissue damage, leading to inflammatory disorders such as inflammatory bowel diseases. Several unique subsets of intestinal innate immune...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2012-03, Vol.109 (13), p.5010
Hauptverfasser:	Kayama, Hisako, Ueda, Yoshiyasu, Sawa, Yukihisa, Jeon, Seong Gyu, Ma, Ji Su, Okumura, Ryu, Kubo, Atsuko, Ishii, Masaru, Okazaki, Taku, Murakami, Masaaki, Yamamoto, Masahiro, Yagita, Hideo, Takeda, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cytokines Gene expression Inflammatory bowel disease Lymphocytes Rodents T cell receptors
Online-Zugang:	Volltext
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