Association Between Estrogen Receptor-a PvuII and XbaI Gene Polymorphisms With Extracranial Carotid Stenosis
To determine whether estrogen receptor-α (ESR1) PvuII and XbaI gene polymorphisms affect carotid artery atherosclerosis in an Iranian population. There were 445 consecutive patients referred for isolated coronary artery bypass graft (CABG) surgery at our center registered in the study. The subjects...
Gespeichert in:
| Veröffentlicht in: | Laboratory medicine 2011-11, Vol.42 (11), p.663 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 11 |
| container_start_page | 663 |
| container_title | Laboratory medicine |
| container_volume | 42 |
| creator | Boroumand, Mohammadali Ghasemi, Yaghoob Shirani, Shapour Pourgholi, Leila Anvari, Maryam Sotoudeh Sepehriseresht, Saeed Mohammadtaghvaei, Narges Ghaedi, Mahboubeh Sheikhfathollahi, Mahmood Goodarzynejad, Hamidreza |
| description | To determine whether estrogen receptor-α (ESR1) PvuII and XbaI gene polymorphisms affect carotid artery atherosclerosis in an Iranian population. There were 445 consecutive patients referred for isolated coronary artery bypass graft (CABG) surgery at our center registered in the study. The subjects were classified into 2 major categories with (≥50%) and without ( |
| format | Article |
| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_journals_929147073</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2612919221</sourcerecordid><originalsourceid>FETCH-proquest_journals_9291470733</originalsourceid><addsrcrecordid>eNqNis1OwlAQRu9CE8rPO0zcN7m2haZLJRW7I0CiOzKUAS5p79Q7U8G3twsfwNV3Ts73YCJrbR7PbZKPzFjkOmhWLJLINC8iXDtUxx5eSW9EHkrRwOcBNlRTpxxihPV3X1WA_gifB6xgRZ5gzc1Py6G7OGkFPpxeoLxrwDqgd9jAEgOrO8JWybM4mZrHEzZCs7-dmKe3crd8j7vAXz2J7q_cBz-kfZEUz1lu8zT91-kXU8ZIJg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>929147073</pqid></control><display><type>article</type><title>Association Between Estrogen Receptor-a PvuII and XbaI Gene Polymorphisms With Extracranial Carotid Stenosis</title><source>Oxford University Press</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><creator>Boroumand, Mohammadali ; Ghasemi, Yaghoob ; Shirani, Shapour ; Pourgholi, Leila ; Anvari, Maryam Sotoudeh ; Sepehriseresht, Saeed ; Mohammadtaghvaei, Narges ; Ghaedi, Mahboubeh ; Sheikhfathollahi, Mahmood ; Goodarzynejad, Hamidreza</creator><creatorcontrib>Boroumand, Mohammadali ; Ghasemi, Yaghoob ; Shirani, Shapour ; Pourgholi, Leila ; Anvari, Maryam Sotoudeh ; Sepehriseresht, Saeed ; Mohammadtaghvaei, Narges ; Ghaedi, Mahboubeh ; Sheikhfathollahi, Mahmood ; Goodarzynejad, Hamidreza</creatorcontrib><description>To determine whether estrogen receptor-α (ESR1) PvuII and XbaI gene polymorphisms affect carotid artery atherosclerosis in an Iranian population. There were 445 consecutive patients referred for isolated coronary artery bypass graft (CABG) surgery at our center registered in the study. The subjects were classified into 2 major categories with (≥50%) and without (<50%) carotid stenosis. Using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), the presence of PvuII and XbaI polymorphism within the ESR gene were analyzed. Even after controlling for age, male sex, cigarette smoking, dyslipidemia, diabetes, and hypertension in a multivariable analysis, PvuII and XbaI polymorphisms were not found to be associated with the occurrence of carotid stenosis ≥50% (P=0.626 and P=0.992, respectively). Our data suggests that ESR1 PvuII and XbaI gene polymorphisms did not have an effect on carotid artery stenosis in an Iranian population undergoing CABG.</description><identifier>ISSN: 0007-5027</identifier><language>eng</language><publisher>Chicago: Oxford University Press</publisher><subject>Cardiovascular disease ; Cholesterol ; Genes ; Studies ; Womens health</subject><ispartof>Laboratory medicine, 2011-11, Vol.42 (11), p.663</ispartof><rights>Copyright American Society for Clinical Pathology Nov 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Boroumand, Mohammadali</creatorcontrib><creatorcontrib>Ghasemi, Yaghoob</creatorcontrib><creatorcontrib>Shirani, Shapour</creatorcontrib><creatorcontrib>Pourgholi, Leila</creatorcontrib><creatorcontrib>Anvari, Maryam Sotoudeh</creatorcontrib><creatorcontrib>Sepehriseresht, Saeed</creatorcontrib><creatorcontrib>Mohammadtaghvaei, Narges</creatorcontrib><creatorcontrib>Ghaedi, Mahboubeh</creatorcontrib><creatorcontrib>Sheikhfathollahi, Mahmood</creatorcontrib><creatorcontrib>Goodarzynejad, Hamidreza</creatorcontrib><title>Association Between Estrogen Receptor-a PvuII and XbaI Gene Polymorphisms With Extracranial Carotid Stenosis</title><title>Laboratory medicine</title><description>To determine whether estrogen receptor-α (ESR1) PvuII and XbaI gene polymorphisms affect carotid artery atherosclerosis in an Iranian population. There were 445 consecutive patients referred for isolated coronary artery bypass graft (CABG) surgery at our center registered in the study. The subjects were classified into 2 major categories with (≥50%) and without (<50%) carotid stenosis. Using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), the presence of PvuII and XbaI polymorphism within the ESR gene were analyzed. Even after controlling for age, male sex, cigarette smoking, dyslipidemia, diabetes, and hypertension in a multivariable analysis, PvuII and XbaI polymorphisms were not found to be associated with the occurrence of carotid stenosis ≥50% (P=0.626 and P=0.992, respectively). Our data suggests that ESR1 PvuII and XbaI gene polymorphisms did not have an effect on carotid artery stenosis in an Iranian population undergoing CABG.</description><subject>Cardiovascular disease</subject><subject>Cholesterol</subject><subject>Genes</subject><subject>Studies</subject><subject>Womens health</subject><issn>0007-5027</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNis1OwlAQRu9CE8rPO0zcN7m2haZLJRW7I0CiOzKUAS5p79Q7U8G3twsfwNV3Ts73YCJrbR7PbZKPzFjkOmhWLJLINC8iXDtUxx5eSW9EHkrRwOcBNlRTpxxihPV3X1WA_gifB6xgRZ5gzc1Py6G7OGkFPpxeoLxrwDqgd9jAEgOrO8JWybM4mZrHEzZCs7-dmKe3crd8j7vAXz2J7q_cBz-kfZEUz1lu8zT91-kXU8ZIJg</recordid><startdate>20111101</startdate><enddate>20111101</enddate><creator>Boroumand, Mohammadali</creator><creator>Ghasemi, Yaghoob</creator><creator>Shirani, Shapour</creator><creator>Pourgholi, Leila</creator><creator>Anvari, Maryam Sotoudeh</creator><creator>Sepehriseresht, Saeed</creator><creator>Mohammadtaghvaei, Narges</creator><creator>Ghaedi, Mahboubeh</creator><creator>Sheikhfathollahi, Mahmood</creator><creator>Goodarzynejad, Hamidreza</creator><general>Oxford University Press</general><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20111101</creationdate><title>Association Between Estrogen Receptor-a PvuII and XbaI Gene Polymorphisms With Extracranial Carotid Stenosis</title><author>Boroumand, Mohammadali ; Ghasemi, Yaghoob ; Shirani, Shapour ; Pourgholi, Leila ; Anvari, Maryam Sotoudeh ; Sepehriseresht, Saeed ; Mohammadtaghvaei, Narges ; Ghaedi, Mahboubeh ; Sheikhfathollahi, Mahmood ; Goodarzynejad, Hamidreza</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_9291470733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Cardiovascular disease</topic><topic>Cholesterol</topic><topic>Genes</topic><topic>Studies</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boroumand, Mohammadali</creatorcontrib><creatorcontrib>Ghasemi, Yaghoob</creatorcontrib><creatorcontrib>Shirani, Shapour</creatorcontrib><creatorcontrib>Pourgholi, Leila</creatorcontrib><creatorcontrib>Anvari, Maryam Sotoudeh</creatorcontrib><creatorcontrib>Sepehriseresht, Saeed</creatorcontrib><creatorcontrib>Mohammadtaghvaei, Narges</creatorcontrib><creatorcontrib>Ghaedi, Mahboubeh</creatorcontrib><creatorcontrib>Sheikhfathollahi, Mahmood</creatorcontrib><creatorcontrib>Goodarzynejad, Hamidreza</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Laboratory medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boroumand, Mohammadali</au><au>Ghasemi, Yaghoob</au><au>Shirani, Shapour</au><au>Pourgholi, Leila</au><au>Anvari, Maryam Sotoudeh</au><au>Sepehriseresht, Saeed</au><au>Mohammadtaghvaei, Narges</au><au>Ghaedi, Mahboubeh</au><au>Sheikhfathollahi, Mahmood</au><au>Goodarzynejad, Hamidreza</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association Between Estrogen Receptor-a PvuII and XbaI Gene Polymorphisms With Extracranial Carotid Stenosis</atitle><jtitle>Laboratory medicine</jtitle><date>2011-11-01</date><risdate>2011</risdate><volume>42</volume><issue>11</issue><spage>663</spage><pages>663-</pages><issn>0007-5027</issn><abstract>To determine whether estrogen receptor-α (ESR1) PvuII and XbaI gene polymorphisms affect carotid artery atherosclerosis in an Iranian population. There were 445 consecutive patients referred for isolated coronary artery bypass graft (CABG) surgery at our center registered in the study. The subjects were classified into 2 major categories with (≥50%) and without (<50%) carotid stenosis. Using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), the presence of PvuII and XbaI polymorphism within the ESR gene were analyzed. Even after controlling for age, male sex, cigarette smoking, dyslipidemia, diabetes, and hypertension in a multivariable analysis, PvuII and XbaI polymorphisms were not found to be associated with the occurrence of carotid stenosis ≥50% (P=0.626 and P=0.992, respectively). Our data suggests that ESR1 PvuII and XbaI gene polymorphisms did not have an effect on carotid artery stenosis in an Iranian population undergoing CABG.</abstract><cop>Chicago</cop><pub>Oxford University Press</pub></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-5027 |
| ispartof | Laboratory medicine, 2011-11, Vol.42 (11), p.663 |
| issn | 0007-5027 |
| language | eng |
| recordid | cdi_proquest_journals_929147073 |
| source | Oxford University Press; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | Cardiovascular disease Cholesterol Genes Studies Womens health |
| title | Association Between Estrogen Receptor-a PvuII and XbaI Gene Polymorphisms With Extracranial Carotid Stenosis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T19%3A27%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20Between%20Estrogen%20Receptor-a%20PvuII%20and%20XbaI%20Gene%20Polymorphisms%20With%20Extracranial%20Carotid%20Stenosis&rft.jtitle=Laboratory%20medicine&rft.au=Boroumand,%20Mohammadali&rft.date=2011-11-01&rft.volume=42&rft.issue=11&rft.spage=663&rft.pages=663-&rft.issn=0007-5027&rft_id=info:doi/&rft_dat=%3Cproquest%3E2612919221%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=929147073&rft_id=info:pmid/&rfr_iscdi=true |