Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental

Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that...

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Veröffentlicht in:Tropical medicine & international health 2012-03, Vol.17 (3), p.374
Hauptverfasser: Park, Paul H, Magut, Cornelius, Gardner, Adrian, O'yiengo, Dennis O, Kamle, Lydia, Langat, Bernard K, Buziba, Nathan G, Carter, E. Jane
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container_issue 3
container_start_page 374
container_title Tropical medicine & international health
container_volume 17
creator Park, Paul H
Magut, Cornelius
Gardner, Adrian
O'yiengo, Dennis O
Kamle, Lydia
Langat, Bernard K
Buziba, Nathan G
Carter, E. Jane
description Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that attempts to overcome diagnostic delivery barriers. Methods: Review of the public DST program identified several barriers limiting access: lack of program awareness amongst physicians, limited supplies, unreliable transport and no specimen tracking methods. Staff visited 19 clinic sites in western Kenya and trained healthcare providers in regard to the novel diagnostics model. Provincial laboratory registries were reviewed to assess utilization of DST services prior to and after program modification. Results: Onsite training consisted of the inclusion criteria for re-treatment patients - the high-priority group for DST. Additionally, infrastructural support established a stable supply chain. An existing transport system was adapted to deliver sputum specimens. Task shifting created an accession and tracking system of specimens. During the 24months post-implementation, the number of re-treatment specimens from the catchment area increased from 9.1 to 23.5 specimens per month. In comparing annual data pre- and post-implementation, the proportion of re-treatment cases receiving DST increased from 24.7% (n =403) to 32.5% (n =574) (P
doi_str_mv 10.1111/j.1365-3156.2011.02933.x
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Jane</creator><creatorcontrib>Park, Paul H ; Magut, Cornelius ; Gardner, Adrian ; O'yiengo, Dennis O ; Kamle, Lydia ; Langat, Bernard K ; Buziba, Nathan G ; Carter, E. Jane</creatorcontrib><description>Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that attempts to overcome diagnostic delivery barriers. Methods: Review of the public DST program identified several barriers limiting access: lack of program awareness amongst physicians, limited supplies, unreliable transport and no specimen tracking methods. Staff visited 19 clinic sites in western Kenya and trained healthcare providers in regard to the novel diagnostics model. Provincial laboratory registries were reviewed to assess utilization of DST services prior to and after program modification. Results: Onsite training consisted of the inclusion criteria for re-treatment patients - the high-priority group for DST. Additionally, infrastructural support established a stable supply chain. An existing transport system was adapted to deliver sputum specimens. Task shifting created an accession and tracking system of specimens. During the 24months post-implementation, the number of re-treatment specimens from the catchment area increased from 9.1 to 23.5 specimens per month. In comparing annual data pre- and post-implementation, the proportion of re-treatment cases receiving DST increased from 24.7% (n =403) to 32.5% (n =574) (P &lt;0.001), and the number of multidrug-resistant (MDR) TB cases increased from 5 to 10 cases. Conclusion: The delivery model significantly increased the proportion of re-treatment cases receiving DST. 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Jane</creatorcontrib><title>Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental</title><title>Tropical medicine &amp; international health</title><description>Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that attempts to overcome diagnostic delivery barriers. 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subjects Drug resistance
Health care delivery
Medical laboratories
Medical tests
Tuberculosis
title Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental
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