Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental
Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that...
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creator | Park, Paul H Magut, Cornelius Gardner, Adrian O'yiengo, Dennis O Kamle, Lydia Langat, Bernard K Buziba, Nathan G Carter, E. Jane |
description | Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that attempts to overcome diagnostic delivery barriers. Methods: Review of the public DST program identified several barriers limiting access: lack of program awareness amongst physicians, limited supplies, unreliable transport and no specimen tracking methods. Staff visited 19 clinic sites in western Kenya and trained healthcare providers in regard to the novel diagnostics model. Provincial laboratory registries were reviewed to assess utilization of DST services prior to and after program modification. Results: Onsite training consisted of the inclusion criteria for re-treatment patients - the high-priority group for DST. Additionally, infrastructural support established a stable supply chain. An existing transport system was adapted to deliver sputum specimens. Task shifting created an accession and tracking system of specimens. During the 24months post-implementation, the number of re-treatment specimens from the catchment area increased from 9.1 to 23.5 specimens per month. In comparing annual data pre- and post-implementation, the proportion of re-treatment cases receiving DST increased from 24.7% (n =403) to 32.5% (n =574) (P |
doi_str_mv | 10.1111/j.1365-3156.2011.02933.x |
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Jane</creator><creatorcontrib>Park, Paul H ; Magut, Cornelius ; Gardner, Adrian ; O'yiengo, Dennis O ; Kamle, Lydia ; Langat, Bernard K ; Buziba, Nathan G ; Carter, E. Jane</creatorcontrib><description>Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that attempts to overcome diagnostic delivery barriers. Methods: Review of the public DST program identified several barriers limiting access: lack of program awareness amongst physicians, limited supplies, unreliable transport and no specimen tracking methods. Staff visited 19 clinic sites in western Kenya and trained healthcare providers in regard to the novel diagnostics model. Provincial laboratory registries were reviewed to assess utilization of DST services prior to and after program modification. Results: Onsite training consisted of the inclusion criteria for re-treatment patients - the high-priority group for DST. Additionally, infrastructural support established a stable supply chain. An existing transport system was adapted to deliver sputum specimens. Task shifting created an accession and tracking system of specimens. During the 24months post-implementation, the number of re-treatment specimens from the catchment area increased from 9.1 to 23.5 specimens per month. In comparing annual data pre- and post-implementation, the proportion of re-treatment cases receiving DST increased from 24.7% (n =403) to 32.5% (n =574) (P <0.001), and the number of multidrug-resistant (MDR) TB cases increased from 5 to 10 cases. Conclusion: The delivery model significantly increased the proportion of re-treatment cases receiving DST. Barriers to accessing the national MDR-TB surveillance program can be overcome through an operational model based on pragmatic use of existing services from multiple partners.[PUBLICATION ABSTRACT]</description><identifier>ISSN: 1360-2276</identifier><identifier>EISSN: 1365-3156</identifier><identifier>DOI: 10.1111/j.1365-3156.2011.02933.x</identifier><language>eng</language><publisher>Oxford: Blackwell Publishing Ltd</publisher><subject>Drug resistance ; Health care delivery ; Medical laboratories ; Medical tests ; Tuberculosis</subject><ispartof>Tropical medicine & international health, 2012-03, Vol.17 (3), p.374</ispartof><rights>2011 Blackwell Publishing Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Park, Paul H</creatorcontrib><creatorcontrib>Magut, Cornelius</creatorcontrib><creatorcontrib>Gardner, Adrian</creatorcontrib><creatorcontrib>O'yiengo, Dennis O</creatorcontrib><creatorcontrib>Kamle, Lydia</creatorcontrib><creatorcontrib>Langat, Bernard K</creatorcontrib><creatorcontrib>Buziba, Nathan G</creatorcontrib><creatorcontrib>Carter, E. Jane</creatorcontrib><title>Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental</title><title>Tropical medicine & international health</title><description>Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. We describe and evaluate a novel operational design that attempts to overcome diagnostic delivery barriers. Methods: Review of the public DST program identified several barriers limiting access: lack of program awareness amongst physicians, limited supplies, unreliable transport and no specimen tracking methods. Staff visited 19 clinic sites in western Kenya and trained healthcare providers in regard to the novel diagnostics model. Provincial laboratory registries were reviewed to assess utilization of DST services prior to and after program modification. Results: Onsite training consisted of the inclusion criteria for re-treatment patients - the high-priority group for DST. Additionally, infrastructural support established a stable supply chain. An existing transport system was adapted to deliver sputum specimens. Task shifting created an accession and tracking system of specimens. During the 24months post-implementation, the number of re-treatment specimens from the catchment area increased from 9.1 to 23.5 specimens per month. In comparing annual data pre- and post-implementation, the proportion of re-treatment cases receiving DST increased from 24.7% (n =403) to 32.5% (n =574) (P <0.001), and the number of multidrug-resistant (MDR) TB cases increased from 5 to 10 cases. Conclusion: The delivery model significantly increased the proportion of re-treatment cases receiving DST. Barriers to accessing the national MDR-TB surveillance program can be overcome through an operational model based on pragmatic use of existing services from multiple partners.[PUBLICATION ABSTRACT]</description><subject>Drug resistance</subject><subject>Health care delivery</subject><subject>Medical laboratories</subject><subject>Medical tests</subject><subject>Tuberculosis</subject><issn>1360-2276</issn><issn>1365-3156</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqNj8tOwzAQRQMCiec_jNiwSsijDapYUR4CIYSEukXV4AypK8cGPwr8Dcuu-In8GHbUVLDDC9ujO3PPnSiCLE0yf07mSVaUw7jIhmWSp1mWpPmoKJKPzWh3LWx1_zTO89NyJ9ozZp6m6WAwLHc3nm4l04SGyxqQMTIGrAI7I7i_fIwnYzBOL4gLgZIRvGpVa2y8rpWrZ4DAlJeelUbLFwSNqkgAl_BOxpKWcEfyE8_gnDGt2m-rCcSxx7RLA-h6u4agor8gXwuEyTj2KaD9AqtxQdqAk4HRLkXX8guuJFQojbdXzrOhcmu2a0halJUCn63bUfngQpmejyaYLXjNA5xjqFbbN1RxlJZWYBIqiP1cCNAv7927df34A2O8CkxxEG2_oDB0uHr3o6Prq8nFTewd3kLO6Vw5Lb00HeV5McoKf_-r6QewKqlQ</recordid><startdate>20120301</startdate><enddate>20120301</enddate><creator>Park, Paul H</creator><creator>Magut, Cornelius</creator><creator>Gardner, Adrian</creator><creator>O'yiengo, Dennis O</creator><creator>Kamle, Lydia</creator><creator>Langat, Bernard K</creator><creator>Buziba, Nathan G</creator><creator>Carter, E. Jane</creator><general>Blackwell Publishing Ltd</general><scope>7T2</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope></search><sort><creationdate>20120301</creationdate><title>Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental</title><author>Park, Paul H ; Magut, Cornelius ; Gardner, Adrian ; O'yiengo, Dennis O ; Kamle, Lydia ; Langat, Bernard K ; Buziba, Nathan G ; Carter, E. Jane</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_9223913223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Drug resistance</topic><topic>Health care delivery</topic><topic>Medical laboratories</topic><topic>Medical tests</topic><topic>Tuberculosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Paul H</creatorcontrib><creatorcontrib>Magut, Cornelius</creatorcontrib><creatorcontrib>Gardner, Adrian</creatorcontrib><creatorcontrib>O'yiengo, Dennis O</creatorcontrib><creatorcontrib>Kamle, Lydia</creatorcontrib><creatorcontrib>Langat, Bernard K</creatorcontrib><creatorcontrib>Buziba, Nathan G</creatorcontrib><creatorcontrib>Carter, E. Jane</creatorcontrib><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><jtitle>Tropical medicine & international health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Paul H</au><au>Magut, Cornelius</au><au>Gardner, Adrian</au><au>O'yiengo, Dennis O</au><au>Kamle, Lydia</au><au>Langat, Bernard K</au><au>Buziba, Nathan G</au><au>Carter, E. Jane</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental</atitle><jtitle>Tropical medicine & international health</jtitle><date>2012-03-01</date><risdate>2012</risdate><volume>17</volume><issue>3</issue><spage>374</spage><pages>374-</pages><issn>1360-2276</issn><eissn>1365-3156</eissn><abstract>Objective: Kenya, like many resource-constrained countries, has a single mycobacterial laboratory, centrally located in Nairobi, with capacity for drug-susceptibility testing (DST) - the gold standard in diagnosing drug-resistant tuberculosis. 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subjects | Drug resistance Health care delivery Medical laboratories Medical tests Tuberculosis |
title | Increasing access to the MDR-TB surveillance program through a collaborative model in western Kenya; Accroître l'accès au programme de surveillance de la TB-MDR à travers un modèle de collaboration dans l'ouest du Kenya; Aumentando el acceso a los programas de vigilancia de MDR-TB mediante un modelo de programa colaborativo en Kenia Occidental |
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