Probenecid is a chemosensitizer in cancer cell lines

Resistance and toxicity are the major barriers to successful cancer chemotherapies. Developing molecules that reduce drug resistance and improve antineoplastic effects is of great interest for cancer research; ideally, these substances should not affect the pharmacodynamics of the chemotherapeutic a...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 2012-02, Vol.69 (2), p.495-504
Hauptverfasser:	Campos-Arroyo, Denise, Martínez-Lazcano, Juan Carlos, Melendez-Zajgla, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Pharmaceutic - pharmacology Antineoplastic agents Antineoplastic Agents - pharmacology Apoptosis - drug effects Biological and medical sciences Cancer Research Cell Line, Tumor Cell Survival - drug effects Cisplatin - pharmacology Dose-Response Relationship, Drug Drug Synergism HeLa Cells Humans Medical sciences Medicine Medicine & Public Health Microscopy, Fluorescence Neoplasms - drug therapy Neoplasms - pathology Oncology Original Article Paclitaxel - pharmacology Pharmacology. Drug treatments Pharmacology/Toxicology Probenecid - pharmacology Tumor Stem Cell Assay
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