Magnetic resonance perfusion and spectroscopy in a giant tuberculoma
Magnetic resonance imaging (MRI) of the brain revealed a lobulated T2-weighted hypointense mass lesion in the right cerebellar hemisphere with adjacent vasogenic edema causing mass effect on the fourth ventricle with resultant supratentorial hydrocephalus and periventricular cerebrospinal fluid (CSF...
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| Veröffentlicht in: | Neurology India 2011-11, Vol.59 (6), p.913 |
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| description | Magnetic resonance imaging (MRI) of the brain revealed a lobulated T2-weighted hypointense mass lesion in the right cerebellar hemisphere with adjacent vasogenic edema causing mass effect on the fourth ventricle with resultant supratentorial hydrocephalus and periventricular cerebrospinal fluid (CSF) ooze [Figure 1]a and b. The mass appeared isointense on T1-weighted images with thick irregular peripheral enhancement [Figure 1]c and d. Dynamic contrast-enhanced MRI perfusion revealed the mass to be homogenously hypoperfused as compared to normal reference cerebellar white matter [Figure 2]a. MR-spectroscopy (TE135) revealed absent N-acetyl aspartate (NAA) within the mass lesion with a large lipid peak at 1.2 ppm [Figure 2]b. Multivoxel spectroscopy (TE30) revealed reduction of NAA without significant elevation of choline in the mass lesion [Figure 3]. |
| doi_str_mv | 10.4103/0028-3886.91382 |
| format | Article |
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The mass appeared isointense on T1-weighted images with thick irregular peripheral enhancement [Figure 1]c and d. Dynamic contrast-enhanced MRI perfusion revealed the mass to be homogenously hypoperfused as compared to normal reference cerebellar white matter [Figure 2]a. MR-spectroscopy (TE135) revealed absent N-acetyl aspartate (NAA) within the mass lesion with a large lipid peak at 1.2 ppm [Figure 2]b. Multivoxel spectroscopy (TE30) revealed reduction of NAA without significant elevation of choline in the mass lesion [Figure 3].</description><identifier>ISSN: 0028-3886</identifier><identifier>EISSN: 1998-4022</identifier><identifier>DOI: 10.4103/0028-3886.91382</identifier><identifier>PMID: 22234216</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. 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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Blood Volume Brain Brain tumors Care and treatment Choline - metabolism Diagnosis Drug therapy Humans Lipids Magnetic Resonance Imaging Magnetic Resonance Spectroscopy - methods Male Methods Nuclear magnetic resonance spectroscopy Perfusion (Physiology) Spectrum analysis Tuberculoma - diagnosis Young Adult |
| title | Magnetic resonance perfusion and spectroscopy in a giant tuberculoma |
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